eF-site ID 4zgz-ABCD PDB Code 4zgz Chain A, B, C, D click to enlarge Title STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME Classification PROTEIN BINDING Compound Antizyme inhibitor 1 Source Homo sapiens (Human) (OAZ1_HUMAN) Sequence A:  YSVGLLDEGTDLGNVIDNYVYEHTLTGKNAFFVGDLGKIV KKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFAC SSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVN ILTCDNEIELKKIARNHPNAKVLLHIATEDMKFGTTLKNC RHLLECAKELDVQIIGVKFHVSSACKESQVYVHALSDARC VFDMAGEIGFTMNMLDIGGGFTGTEFQLEEVNHVISPLLD IYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVAFMY YMNDGVYGSFASKLSTIPEVHKKPLFTSSLWGPSCDELDQ IVESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAI YYMMSFSDWYEMQDAGITSDSMMKNFFFV B:  KRINWRTVLSGGSLYIEIPGGALPEGSKDSFAVLLEFAEE QLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLV PKRPDACFMAYTFE C:  YSVGLLDEGTDLGNVIDNYVYEHTLTGKNAFFVGDLGKIV KKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFAC SSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVN ILTCDNEIELKKIARNHPNAKVLLHIATEDMKFGTTLKNC RHLLECAKELDVQIIGVKFHVSSACKESQVYVHALSDARC VFDMAGEIGFTMNMLDIGGGFTGTEFQLEEVNHVISPLLD IYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVAFMY YMNDGVYGSFASKLSTIPEVHKKPLFTSSLWGPSCDELDQ IVESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAI YYMMSFSDWYEMQDAGITSDSMMKNFFFV D:  AKRINWRTVLSGGSLYIEIPGGALPEGSKDSFAVLLEFAE EQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPL VPKRPDACFMAYTFE Description Functional site 1) chain A residue 69 type SITE sequence K description Not modified => ECO:0000250|UniProtKB:O35484 source Swiss-Prot : SWS_FT_FI1 2) chain C residue 69 type SITE sequence K description Not modified => ECO:0000250|UniProtKB:O35484 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 159-167 type prosite sequence LLEFAEEQL description ODC_AZ Ornithine decarboxylase antizyme signature. LLEFAEEQL source prosite : PS01337 4) chain A residue 222-239 type prosite sequence AGEIGFTMNMLDIGGGFT description ODR_DC_2_2 Orn/DAP/Arg decarboxylases family 2 signature 2. AgeigftMnMLDIGGGFT source prosite : PS00879

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