|
eF-site ID
|
4z50-C |
PDB Code
|
4z50 |
Chain
|
C |
|
click to enlarge
|
|
Title
|
Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Tucked Flap |
Classification
|
HYDROLASE |
Compound
|
Protease |
Source
|
(Q0PQ60_9HIV1) |
|
Sequence
|
C: |
PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG
RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT
PVNVIGRDTMTQIGATLNF
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
C |
residue |
7 |
type |
|
sequence |
K
|
description |
binding site for residue CL C 101
|
source |
: AC8
|
|
2)
|
chain |
C |
residue |
8 |
type |
|
sequence |
R
|
description |
binding site for residue CL C 101
|
source |
: AC8
|
|
3)
|
chain |
C |
residue |
21 |
type |
|
sequence |
E
|
description |
binding site for residue CL C 102
|
source |
: AC9
|
|
4)
|
chain |
C |
residue |
8 |
type |
|
sequence |
R
|
description |
binding site for residue CL C 103
|
source |
: AD1
|
|
5)
|
chain |
C |
residue |
60 |
type |
|
sequence |
D
|
description |
binding site for residue NA C 104
|
source |
: AD2
|
|
|
|