|
|
eF-site ID
|
4z50-C |
|
PDB Code
|
4z50 |
|
Chain
|
C |
|
click to enlarge
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|
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Title
|
Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Tucked Flap |
|
Classification
|
HYDROLASE |
|
Compound
|
Protease |
|
Source
|
(Q0PQ60_9HIV1) |
|
|
Sequence
|
C: |
PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG
RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT
PVNVIGRDTMTQIGATLNF
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
7 |
| type |
|
| sequence |
K
|
| description |
binding site for residue CL C 101
|
| source |
: AC8
|
|
|
2)
|
chain |
C |
| residue |
8 |
| type |
|
| sequence |
R
|
| description |
binding site for residue CL C 101
|
| source |
: AC8
|
|
|
3)
|
chain |
C |
| residue |
21 |
| type |
|
| sequence |
E
|
| description |
binding site for residue CL C 102
|
| source |
: AC9
|
|
|
4)
|
chain |
C |
| residue |
8 |
| type |
|
| sequence |
R
|
| description |
binding site for residue CL C 103
|
| source |
: AD1
|
|
|
5)
|
chain |
C |
| residue |
60 |
| type |
|
| sequence |
D
|
| description |
binding site for residue NA C 104
|
| source |
: AD2
|
|
|
|