eF-site ID 4z50-ABCD PDB Code 4z50 Chain A, B, C, D click to enlarge Title Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Tucked Flap Classification HYDROLASE Compound Protease Source (Q0PQ60_9HIV1) Sequence A:  PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT PVNVIGRDTMTQIGATLNF B:  PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT PVNVIGRDTMTQIGATLNF C:  PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT PVNVIGRDTMTQIGATLNF D:  PQITLWKRPFVTVKVGGQLKEALLNTGADNTIFEDINLPG RWKPKMVGGIGGFLKVREYDQVPIEIAGHKVIGTVLVGPT PVNVIGRDTMTQIGATLNF Description Functional site 1) chain A residue 21 type sequence E description binding site for residue CL A 101 source : AC1 2) chain B residue 155 type sequence K description binding site for residue CL B 201 source : AC2 3) chain D residue 106 type sequence W description binding site for residue CL B 201 source : AC2 4) chain B residue 121 type sequence E description binding site for residue CL B 202 source : AC3 5) chain B residue 107 type sequence K description binding site for residue CL B 203 source : AC4 6) chain B residue 108 type sequence R description binding site for residue CL B 203 source : AC4 7) chain B residue 160 type sequence D description binding site for residue NA B 204 source : AC5 8) chain B residue 119 type sequence L description binding site for residue NA B 205 source : AC6 9) chain B residue 112 type sequence T description binding site for residue GOL B 206 source : AC7 10) chain B residue 165 type sequence E description binding site for residue GOL B 206 source : AC7 11) chain B residue 167 type sequence A description binding site for residue GOL B 206 source : AC7 12) chain B residue 168 type sequence G description binding site for residue GOL B 206 source : AC7 13) chain C residue 7 type sequence K description binding site for residue CL C 101 source : AC8 14) chain C residue 8 type sequence R description binding site for residue CL C 101 source : AC8 15) chain C residue 21 type sequence E description binding site for residue CL C 102 source : AC9 16) chain C residue 8 type sequence R description binding site for residue CL C 103 source : AD1 17) chain C residue 60 type sequence D description binding site for residue NA C 104 source : AD2 18) chain D residue 121 type sequence E description binding site for residue CL D 201 source : AD3 19) chain D residue 107 type sequence K description binding site for residue CL D 202 source : AD4 20) chain D residue 108 type sequence R description binding site for residue CL D 202 source : AD4 21) chain D residue 160 type sequence D description binding site for residue NA D 203 source : AD5 22) chain D residue 169 type sequence H description binding site for residue GOL D 204 source : AD6 23) chain D residue 192 type sequence Q description binding site for residue GOL D 204 source : AD6 24) chain D residue 193 type sequence I description binding site for residue GOL D 204 source : AD6

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