|
|
eF-site ID
|
4z2n-A |
|
PDB Code
|
4z2n |
|
Chain
|
A |
|
click to enlarge
|
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Title
|
Crystal structure of human FACT SPT16 middle domain |
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Classification
|
TRANSCRIPTION |
|
Compound
|
FACT complex subunit SPT16 |
|
Source
|
(SP16H_HUMAN) |
|
|
Sequence
|
A: |
VKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVN
GFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLK
NAIMFGKKRHTDVQFYTEVHDRDDLYAEQMEREMRHKLKT
AFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQ
PTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMV
IVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQ
SLNWTKIMKTIVDDPEGFFEQGGWSFLE
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
647 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
2)
|
chain |
A |
| residue |
650 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
658 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
786 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
A |
| residue |
904 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
A |
| residue |
732 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
A |
| residue |
903 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|