eF-site ID 4z2m-H
PDB Code 4z2m
Chain H

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Title Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex
Classification Transcription/DNA binding protein
Compound FACT complex subunit SPT16
Source (H4_HUMAN)
Sequence H:  RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFL
ENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ
Description


Functional site

1) chain H
residue 59
type MOD_RES
sequence K
description N6-glutaryllysine; alternate => ECO:0000269|PubMed:31542297
source Swiss-Prot : SWS_FT_FI10

2) chain H
residue 79
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62806
source Swiss-Prot : SWS_FT_FI11

3) chain H
residue 80
type MOD_RES
sequence T
description Phosphothreonine => ECO:0000250|UniProtKB:P62806
source Swiss-Prot : SWS_FT_FI12

4) chain H
residue 88
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI13

5) chain H
residue 91
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:19818714
source Swiss-Prot : SWS_FT_FI15

6) chain H
residue 59
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
source Swiss-Prot : SWS_FT_FI16

7) chain H
residue 79
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
source Swiss-Prot : SWS_FT_FI16

8) chain H
residue 31
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000269|PubMed:30886146
source Swiss-Prot : SWS_FT_FI17

9) chain H
residue 44
type MOD_RES
sequence K
description N6-propionyllysine; alternate => ECO:0000269|PubMed:17267393
source Swiss-Prot : SWS_FT_FI5

10) chain H
residue 31
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
source Swiss-Prot : SWS_FT_FI6

11) chain H
residue 77
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
source Swiss-Prot : SWS_FT_FI6

12) chain H
residue 91
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
source Swiss-Prot : SWS_FT_FI6

13) chain H
residue 47
type MOD_RES
sequence S
description Phosphoserine; by PAK2 => ECO:0000269|PubMed:21724829, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI8

14) chain H
residue 51
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:20068231
source Swiss-Prot : SWS_FT_FI9


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