eF-site ID 4ylo-F PDB Code 4ylo Chain F click to enlarge Title E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA Classification TRANSCRIPTION/DNA/RNA Compound DNA-directed RNA polymerase subunit alpha Source (4YLO) Sequence F:  AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEID IAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL SDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIK AKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWF NAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIE QVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTN RGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIR QAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGR EPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDED SHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREA KVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALR KLRHPSRSEVLRSFLDD Description (1)  E. coli RNA Polymerase alpha subunit, E. coli RNA Polymerase beta subunit, E. coli RNA Polymerase beta' subunit, E. coli RNA Polymerase omega subunit, E. coli RNA Polymerase sigma70 subunit/DNA Complex Functional site 1) chain F residue 573-592 type DNA_BIND sequence LEEVGKQFDVTRERIRQIEA description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 2) chain F residue 403-416 type prosite sequence DLIQEGNIGLMKAV description SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnIGLMkAV source prosite : PS00715 3) chain F residue 572-598 type prosite sequence TLEEVGKQFDVTRERIRQIEAKALRKL description SIGMA70_2 Sigma-70 factors family signature 2. TleEVGkqfdVTrerIrQIEakaLrkL source prosite : PS00716 4) chain F residue 562 type SITE sequence R description Interaction with anti-sigma factors source Swiss-Prot : SWS_FT_FI2

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