eF-site ID 4ylo-124578ABCDEFGHIJKLMNOPQR PDB Code 4ylo Chain 1, 2, 4, 5, 7, 8, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R Title E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA Classification TRANSCRIPTION/DNA/RNA Compound DNA-directed RNA polymerase subunit alpha Source (4YLO) Sequence 1:  ACTTGACATCCACCTCACGTATGCTATAATGTGTGCAGTC TGACGCGGC 2:  GCCGCGTCAGACTCGTAGGATTATAGCATACGTGAGGTGG ATGTCAAGT 4:  ACTTGACATCCACCTCACGTATGCTATAATGTGTGCAGTC TGACGCGGC 5:  GCCGCGTCAGACTCGTAGGATTATAGCATACGTGAGGTGG ATGTCAAGT 7:  ACTTGACATCCACCTCACGTATGCTATAATGTGTGCAGTC TGACGCGGC 8:  GCCGCGTCAGACTCGTAGGATTATAGCATACGTGAGGTGG ATGTCAAGT A:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVDLR B:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVD C:  VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQ DPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFD VQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQE VYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDK GKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRR RKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMEL VPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDD VKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDL LAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLS ALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVG RMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGE VDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSL GDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPL SEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPI ETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTD EIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGE SSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALM GANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRG GVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQ NTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMR VAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSR DTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGD ILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVP NGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLS EELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELG LTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDD LAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINP IEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAA KGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDL STFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKL GDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDD KMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAY GAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPE SFNVLLKEIRSLGINIELEDE D:  EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERD GLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQ TKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRD IERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGD EFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKR KKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVP LDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRN EKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMAL ELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDE VIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVC AAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPA NGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAE RLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTV GRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGL KPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEII SEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVS KAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSA AQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI STHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDC GTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTA DILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGV CAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRT FHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLV ITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGG ETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELT GLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTD MPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDI TGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRR LVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGP EAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIE VIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEA NGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTE AAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRA AG E:  ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPE ENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQ AVTAIAEGRR F:  AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEID IAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL SDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIK AKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWF NAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIE QVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTN RGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIR QAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGR EPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDED SHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREA KVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALR KLRHPSRSEVLRSFLDD G:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVDLR H:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVD I:  VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQ DPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFD VQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQE VYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDK GKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRR RKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMEL VPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDD VKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDL LAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLS ALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVG RMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGE VDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSL GDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPL SEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPI ETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTD EIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGE SSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALM GANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRG GVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQ NTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMR VAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSR DTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGD ILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVP NGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLS EELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELG LTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDD LAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINP IEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAA KGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDL STFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKL GDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDD KMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAY GAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPE SFNVLLKEIRSLGINIELEDE J:  EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERD GLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQ TKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRD IERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGD EFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKR KKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVP LDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRN EKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMAL ELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDE VIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVC AAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPA NGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAE RLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTV GRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGL KPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEII SEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVS KAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSA AQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI STHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDC GTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTA DILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGV CAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRT FHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLV ITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGG ETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELT GLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTD MPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDI TGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRR LVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGP EAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIE VIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEA NGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTE AAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRA AG K:  ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPE ENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQ AVTAIAEGRR L:  AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEID IAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL SDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIK AKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWF NAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIE QVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTN RGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIR QAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGR EPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDED SHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREA KVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALR KLRHPSRSEVLRSFLDD M:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVDLR N:  TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRR ILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNL KGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVK PQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDE RPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEM ETNGTIDPEEAIRRAATILAEQLEAFVD O:  VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQ DPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFD VQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQE VYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDK GKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRR RKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMEL VPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDD VKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDL LAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLS ALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVG RMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGE VDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSL GDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPL SEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPI ETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTD EIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGE SSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALM GANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRG GVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQ NTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMR VAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSR DTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGD ILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVP NGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLS EELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELG LTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDD LAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINP IEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAA KGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDL STFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKL GDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDD KMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAY GAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPE SFNVLLKEIRSLGINIELEDE P:  EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERD GLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQ TKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRD IERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGD EFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKR KKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVP LDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRN EKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMAL ELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDE VIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVC AAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPA NGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAE RLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTV GRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGL KPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEII SEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVS KAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSA AQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI STHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDC GTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTA DILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGV CAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRT FHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLV ITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGG ETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELT GLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTD MPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDI TGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRR LVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGP EAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIE VIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEA NGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTE AAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRA AG Q:  ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPE ENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQ AVTAIAEGRR R:  AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEID IAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL SDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIK AKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWF NAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIE QVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTN RGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIR QAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGR EPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDED SHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREA KVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALR KLRHPSRSEVLRSFLDD Description (1)  E. coli RNA Polymerase alpha subunit, E. coli RNA Polymerase beta subunit, E. coli RNA Polymerase beta' subunit, E. coli RNA Polymerase omega subunit, E. coli RNA Polymerase sigma70 subunit/DNA Complex Functional site 1) chain C residue 678 type sequence R description binding site for residue MG C 1401 source : AC1 2) chain C residue 814 type sequence D description binding site for residue MG C 1401 source : AC1 3) chain C residue 1106 type sequence R description binding site for residue MG C 1401 source : AC1 4) chain D residue 462 type sequence D description binding site for residue MG C 1401 source : AC1 5) chain D residue 70 type sequence C description binding site for residue ZN D 1501 source : AC2 6) chain D residue 72 type sequence C description binding site for residue ZN D 1501 source : AC2 7) chain D residue 85 type sequence C description binding site for residue ZN D 1501 source : AC2 8) chain D residue 88 type sequence C description binding site for residue ZN D 1501 source : AC2 9) chain D residue 814 type sequence C description binding site for residue ZN D 1502 source : AC3 10) chain D residue 883 type sequence R description binding site for residue ZN D 1502 source : AC3 11) chain D residue 888 type sequence C description binding site for residue ZN D 1502 source : AC3 12) chain D residue 895 type sequence C description binding site for residue ZN D 1502 source : AC3 13) chain D residue 898 type sequence C description binding site for residue ZN D 1502 source : AC3 14) chain J residue 70 type sequence C description binding site for residue ZN J 1501 source : AC4 15) chain J residue 72 type sequence C description binding site for residue ZN J 1501 source : AC4 16) chain J residue 74 type sequence K description binding site for residue ZN J 1501 source : AC4 17) chain J residue 85 type sequence C description binding site for residue ZN J 1501 source : AC4 18) chain J residue 88 type sequence C description binding site for residue ZN J 1501 source : AC4 19) chain J residue 814 type sequence C description binding site for residue ZN J 1502 source : AC5 20) chain J residue 883 type sequence R description binding site for residue ZN J 1502 source : AC5 21) chain J residue 888 type sequence C description binding site for residue ZN J 1502 source : AC5 22) chain J residue 890 type sequence T description binding site for residue ZN J 1502 source : AC5 23) chain J residue 895 type sequence C description binding site for residue ZN J 1502 source : AC5 24) chain J residue 898 type sequence C description binding site for residue ZN J 1502 source : AC5 25) chain J residue 460 type sequence D description binding site for residue MG J 1503 source : AC6 26) chain J residue 462 type sequence D description binding site for residue MG J 1503 source : AC6 27) chain J residue 464 type sequence D description binding site for residue MG J 1503 source : AC6 28) chain P residue 70 type sequence C description binding site for residue ZN P 1501 source : AC7 29) chain P residue 72 type sequence C description binding site for residue ZN P 1501 source : AC7 30) chain P residue 85 type sequence C description binding site for residue ZN P 1501 source : AC7 31) chain P residue 88 type sequence C description binding site for residue ZN P 1501 source : AC7 32) chain P residue 814 type sequence C description binding site for residue ZN P 1502 source : AC8 33) chain P residue 883 type sequence R description binding site for residue ZN P 1502 source : AC8 34) chain P residue 888 type sequence C description binding site for residue ZN P 1502 source : AC8 35) chain P residue 895 type sequence C description binding site for residue ZN P 1502 source : AC8 36) chain P residue 898 type sequence C description binding site for residue ZN P 1502 source : AC8 37) chain P residue 460 type sequence D description binding site for residue MG P 1503 source : AC9 38) chain P residue 462 type sequence D description binding site for residue MG P 1503 source : AC9 39) chain P residue 464 type sequence D description binding site for residue MG P 1503 source : AC9 40) chain 2 residue 16 type sequence C description binding site for nucleotide GTP 3 13 source : AD1 41) chain 2 residue 17 type sequence G description binding site for nucleotide GTP 3 13 source : AD1 42) chain C residue 513 type sequence Q description binding site for nucleotide GTP 3 13 source : AD1 43) chain C residue 529 type sequence R description binding site for nucleotide GTP 3 13 source : AD1 44) chain C residue 564 type sequence P description binding site for nucleotide GTP 3 13 source : AD1 45) chain C residue 568 type sequence N description binding site for nucleotide GTP 3 13 source : AD1 46) chain C residue 572 type sequence I description binding site for nucleotide GTP 3 13 source : AD1 47) chain C residue 684 type sequence N description binding site for nucleotide GTP 3 13 source : AD1 48) chain C residue 688 type sequence Q description binding site for nucleotide GTP 3 13 source : AD1 49) chain C residue 1065 type sequence K description binding site for nucleotide GTP 3 13 source : AD1 50) chain D residue 463 type sequence G description binding site for nucleotide GTP 3 13 source : AD1 51) chain 5 residue 15 type sequence T description binding site for nucleotide GTP 6 13 source : AD2 52) chain 5 residue 16 type sequence C description binding site for nucleotide GTP 6 13 source : AD2 53) chain 5 residue 17 type sequence G description binding site for nucleotide GTP 6 13 source : AD2 54) chain I residue 529 type sequence R description binding site for nucleotide GTP 6 13 source : AD2 55) chain I residue 564 type sequence P description binding site for nucleotide GTP 6 13 source : AD2 56) chain I residue 568 type sequence N description binding site for nucleotide GTP 6 13 source : AD2 57) chain I residue 688 type sequence Q description binding site for nucleotide GTP 6 13 source : AD2 58) chain I residue 1065 type sequence K description binding site for nucleotide GTP 6 13 source : AD2 59) chain J residue 463 type sequence G description binding site for nucleotide GTP 6 13 source : AD2 60) chain 8 residue 15 type sequence T description binding site for nucleotide GTP 9 13 source : AD3 61) chain 8 residue 16 type sequence C description binding site for nucleotide GTP 9 13 source : AD3 62) chain 8 residue 17 type sequence G description binding site for nucleotide GTP 9 13 source : AD3 63) chain O residue 564 type sequence P description binding site for nucleotide GTP 9 13 source : AD3 64) chain O residue 568 type sequence N description binding site for nucleotide GTP 9 13 source : AD3 65) chain O residue 688 type sequence Q description binding site for nucleotide GTP 9 13 source : AD3 66) chain O residue 1065 type sequence K description binding site for nucleotide GTP 9 13 source : AD3 67) chain P residue 463 type sequence G description binding site for nucleotide GTP 9 13 source : AD3 68) chain F residue 573-592 type DNA_BIND sequence LEEVGKQFDVTRERIRQIEA description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 69) chain L residue 573-592 type DNA_BIND sequence LEEVGKQFDVTRERIRQIEA description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 70) chain R residue 573-592 type DNA_BIND sequence LEEVGKQFDVTRERIRQIEA description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 71) chain D residue 88 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 72) chain J residue 72 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 73) chain J residue 85 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 74) chain J residue 88 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 75) chain J residue 460 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 76) chain J residue 462 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 77) chain J residue 464 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 78) chain J residue 814 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 79) chain J residue 888 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 80) chain J residue 895 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 81) chain J residue 898 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 82) chain P residue 70 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 83) chain P residue 72 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 84) chain P residue 85 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 85) chain P residue 88 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 86) chain P residue 460 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 87) chain P residue 462 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 88) chain P residue 464 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 89) chain P residue 814 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 90) chain P residue 888 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 91) chain P residue 895 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 92) chain P residue 898 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 93) chain D residue 895 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 94) chain D residue 898 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 95) chain J residue 70 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 96) chain D residue 460 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 97) chain D residue 462 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 98) chain D residue 464 type DNA_BIND sequence D description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 99) chain D residue 814 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 100) chain D residue 888 type DNA_BIND sequence C description H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963 source Swiss-Prot : SWS_FT_FI1 101) chain C residue 1063-1075 type prosite sequence GDKMAGRHGNKGV description RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV source prosite : PS01166 102) chain F residue 403-416 type prosite sequence DLIQEGNIGLMKAV description SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnIGLMkAV source prosite : PS00715 103) chain F residue 572-598 type prosite sequence TLEEVGKQFDVTRERIRQIEAKALRKL description SIGMA70_2 Sigma-70 factors family signature 2. TleEVGkqfdVTrerIrQIEakaLrkL source prosite : PS00716 104) chain F residue 562 type SITE sequence R description Interaction with anti-sigma factors source Swiss-Prot : SWS_FT_FI2 105) chain L residue 562 type SITE sequence R description Interaction with anti-sigma factors source Swiss-Prot : SWS_FT_FI2 106) chain R residue 562 type SITE sequence R description Interaction with anti-sigma factors source Swiss-Prot : SWS_FT_FI2 107) chain D residue 983 type MOD_RES sequence K description N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01322, ECO:0000269|PubMed:18723842 source Swiss-Prot : SWS_FT_FI3 108) chain J residue 983 type MOD_RES sequence K description N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01322, ECO:0000269|PubMed:18723842 source Swiss-Prot : SWS_FT_FI3 109) chain P residue 983 type MOD_RES sequence K description N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01322, ECO:0000269|PubMed:18723842 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links