eF-site ID 4yko-A
PDB Code 4yko
Chain A

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Title Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32Y:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution
Classification TRANSPORT PROTEIN
Compound Cellular retinoic acid-binding protein 2
Source Homo sapiens (Human) (RABP2_HUMAN)
Sequence A:  PNQSGNWKIIRSENFEELLKVLGVNVMLRKIYVAAASKQA
VEIKQEGDTFYIKVSTTVYTTEINFKVGEEFEEQTVDGRP
CKSLVKWESENKMVCEQKLLKGEGPKTSWTKELTNDGELI
LTMTADDVVCTQVFVRE
Description


Functional site

1) chain A
residue 32
type
sequence Y
description binding site for residue RET A 201
source : AC1

2) chain A
residue 36
type
sequence A
description binding site for residue RET A 201
source : AC1

3) chain A
residue 52
type
sequence I
description binding site for residue RET A 201
source : AC1

4) chain A
residue 54
type
sequence V
description binding site for residue RET A 201
source : AC1

5) chain A
residue 56
type
sequence T
description binding site for residue RET A 201
source : AC1

6) chain A
residue 76
type
sequence V
description binding site for residue RET A 201
source : AC1

7) chain A
residue 109
type
sequence W
description binding site for residue RET A 201
source : AC1

8) chain A
residue 111
type
sequence K
description binding site for residue RET A 201
source : AC1

9) chain A
residue 132
type BINDING
sequence Q
description BINDING => ECO:0000269|PubMed:16979656, ECO:0007744|PDB:2FR3
source Swiss-Prot : SWS_FT_FI1

10) chain A
residue 5-22
type prosite
sequence GNWKIIRSENFEELLKVL
description FABP Cytosolic fatty-acid binding proteins signature. GNWkIirSeNFEeLLKVL
source prosite : PS00214

11) chain A
residue 101
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:21998312
source Swiss-Prot : SWS_FT_FI2


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