eF-site ID 4yhz-P
PDB Code 4yhz
Chain P

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Title Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide
Classification IMMUNE SYSTEM
Compound Fab Heavy Chain
Source (4YHZ)
Sequence P:  ARTXQTARK
Description


Functional site

1) chain P
residue 4
type
sequence X
description binding site for residue GOL H 302
source : AC2

2) chain P
residue 6
type
sequence T
description binding site for residue GOL H 302
source : AC2

3) chain P
residue 3
type
sequence T
description binding site for Ligand residues M3L P 4 through GLN P 5 bound to THR P 3
source : AC9

4) chain P
residue 6
type
sequence T
description binding site for Ligand residues M3L P 4 through GLN P 5 bound to THR P 3
source : AC9

5) chain P
residue 6
type
sequence T
description binding site for Ligand residues M3L P 4 through GLN P 5 bound to THR P 3
source : AC9

6) chain P
residue 7
type
sequence A
description binding site for Ligand residues M3L P 4 through GLN P 5 bound to THR P 3
source : AC9

7) chain P
residue 2
type MOD_RES
sequence R
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1

8) chain P
residue 3
type MOD_RES
sequence T
description Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088
source Swiss-Prot : SWS_FT_FI2

9) chain P
residue 4
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI3

10) chain P
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
source Swiss-Prot : SWS_FT_FI4

11) chain P
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790
source Swiss-Prot : SWS_FT_FI5

12) chain P
residue 8
type MOD_RES
sequence R
description Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433
source Swiss-Prot : SWS_FT_FI6

13) chain P
residue 9
type MOD_RES
sequence K
description N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI7


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