eF-site ID 4yho-HL PDB Code 4yho Chain H, L click to enlarge Title Reversal Agent for Dabigatran Classification IMMUNE SYSTEM Compound aDabi-Fab3 heavy chain Source (4YHO) Sequence H:  QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYYMHWVRQA PGQGLEWMGETNPRNGGTTYNEKFKGKATMTRDTSTSTAY MELSSLRSEDTAVYYCTIGTSGWDYFDYWGQGTLVTVSSA STKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTY ICNVNHKPSNTKVDKKVEPKSC L:  DIVMTQTPLSLSVTPGQPASISCRSSQSIVHSDGNIYLEW YLQKPGQSPKLLIYKVSYRFSGVPDRFSGSGSGTDFTLKI SRVEAEDVGVYYCFQASHVPYTFGQGTKLEIKRTVAAPSV FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE VTHQGLSSPVTKSFNRGEC Description Functional site 1) chain H residue 30 type sequence T description binding site for residue 4CC H 301 source : AC1 2) chain H residue 31 type sequence D description binding site for residue 4CC H 301 source : AC1 3) chain H residue 33 type sequence Y description binding site for residue 4CC H 301 source : AC1 4) chain H residue 35 type sequence H description binding site for residue 4CC H 301 source : AC1 5) chain H residue 50 type sequence E description binding site for residue 4CC H 301 source : AC1 6) chain H residue 52 type sequence N description binding site for residue 4CC H 301 source : AC1 7) chain H residue 54 type sequence R description binding site for residue 4CC H 301 source : AC1 8) chain H residue 102 type sequence G description binding site for residue 4CC H 301 source : AC1 9) chain H residue 103 type sequence W description binding site for residue 4CC H 301 source : AC1 10) chain H residue 104 type sequence D description binding site for residue 4CC H 301 source : AC1 11) chain H residue 105 type sequence Y description binding site for residue 4CC H 301 source : AC1 12) chain H residue 106 type sequence F description binding site for residue 4CC H 301 source : AC1 13) chain L residue 39 type sequence E description binding site for residue 4CC H 301 source : AC1 14) chain L residue 94 type sequence F description binding site for residue 4CC H 301 source : AC1 15) chain L residue 96 type sequence A description binding site for residue 4CC H 301 source : AC1 16) chain L residue 197-203 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 17) chain H residue 200-206 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290

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