eF-site ID 4y7i-AB PDB Code 4y7i Chain A, B click to enlarge Title Crystal Structure of MTMR8 Classification HYDROLASE Compound Myotubularin-related protein 8 Source Homo sapiens (Human) (MTMR8_HUMAN) Sequence A:  SGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPE IVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICR CSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPK LNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQ KLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFIT KAVKVEKASVLVHSSDGWDRTAQVCSVASILLDPFYRTFK GLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLD CIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQ KDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVL NPSTVPYNIQFWCGMYNRF B:  SGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPE IVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICR CSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPK LNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQ KLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFIT KAVKVEKASVLVHSSDGWDRTAQVCSVASILLDPFYRTFK GLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLD CIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQ KDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVL NPSTVPYNIQFWCGMYNRF Description Functional site 1) chain A residue 242 type sequence R description binding site for residue PO4 A 601 source : AC1 2) chain A residue 250 type sequence N description binding site for residue PO4 A 601 source : AC1 3) chain A residue 275 type sequence N description binding site for residue PO4 A 601 source : AC1 4) chain A residue 339 type sequence S description binding site for residue PO4 A 601 source : AC1 5) chain A residue 344 type sequence R description binding site for residue PO4 A 601 source : AC1 6) chain A residue 451 type sequence R description binding site for residue PO4 A 601 source : AC1 7) chain A residue 338 type sequence S description binding site for residue PO4 A 602 source : AC2 8) chain A residue 339 type sequence S description binding site for residue PO4 A 602 source : AC2 9) chain A residue 340 type sequence D description binding site for residue PO4 A 602 source : AC2 10) chain A residue 341 type sequence G description binding site for residue PO4 A 602 source : AC2 11) chain A residue 342 type sequence W description binding site for residue PO4 A 602 source : AC2 12) chain A residue 343 type sequence D description binding site for residue PO4 A 602 source : AC2 13) chain A residue 344 type sequence R description binding site for residue PO4 A 602 source : AC2 14) chain B residue 338 type sequence S description binding site for residue PO4 B 601 source : AC3 15) chain B residue 339 type sequence S description binding site for residue PO4 B 601 source : AC3 16) chain B residue 340 type sequence D description binding site for residue PO4 B 601 source : AC3 17) chain B residue 341 type sequence G description binding site for residue PO4 B 601 source : AC3 18) chain B residue 342 type sequence W description binding site for residue PO4 B 601 source : AC3 19) chain B residue 343 type sequence D description binding site for residue PO4 B 601 source : AC3 20) chain B residue 344 type sequence R description binding site for residue PO4 B 601 source : AC3 21) chain B residue 242 type sequence R description binding site for residue PO4 B 602 source : AC4 22) chain B residue 246 type sequence N description binding site for residue PO4 B 602 source : AC4 23) chain B residue 250 type sequence N description binding site for residue PO4 B 602 source : AC4 24) chain B residue 275 type sequence N description binding site for residue PO4 B 602 source : AC4 25) chain B residue 339 type sequence S description binding site for residue PO4 B 602 source : AC4 26) chain B residue 344 type sequence R description binding site for residue PO4 B 602 source : AC4 27) chain B residue 455 type sequence K description binding site for residue PO4 B 602 source : AC4 28) chain A residue 250 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16959974 source Swiss-Prot : SWS_FT_FI2 29) chain A residue 338 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16959974 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 250 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16959974 source Swiss-Prot : SWS_FT_FI2 31) chain B residue 338 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16959974 source Swiss-Prot : SWS_FT_FI2 32) chain A residue 338 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU10044 source Swiss-Prot : SWS_FT_FI1 33) chain B residue 338 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU10044 source Swiss-Prot : SWS_FT_FI1 34) chain A residue 275 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:Q13614 source Swiss-Prot : SWS_FT_FI3 35) chain A residue 384 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:Q13614 source Swiss-Prot : SWS_FT_FI3 36) chain B residue 275 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:Q13614 source Swiss-Prot : SWS_FT_FI3 37) chain B residue 384 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:Q13614 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links