eF-site ID 4xfs-B PDB Code 4xfs Chain B click to enlarge Title Structure of IL-18 SER Mutant I Classification CYTOKINE Compound Interleukin-18 Source (IL18_HUMAN) Sequence B:  YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRD NAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKI ISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSY EGYFLACEKERDLFKLILAAADAAGDRSIMFTVQNED Description Functional site 1) chain B residue 109 type sequence H description binding site for residue DMS A 202 source : AC2 2) chain B residue 58 type sequence R description binding site for residue GOL A 204 source : AC4 3) chain B residue 59 type sequence G description binding site for residue GOL A 204 source : AC4 4) chain B residue 104 type sequence R description binding site for residue GOL A 204 source : AC4 5) chain B residue 114 type sequence Q description binding site for residue DMS B 201 source : AC5 6) chain B residue 142 type sequence D description binding site for residue DMS B 201 source : AC5 7) chain B residue 143 type sequence A description binding site for residue DMS B 201 source : AC5 8) chain B residue 144 type sequence A description binding site for residue DMS B 201 source : AC5 9) chain B residue 149 type sequence I description binding site for residue DMS B 201 source : AC5 10) chain B residue 146 type sequence D description binding site for residue DMS B 202 source : AC6 11) chain B residue 70 type sequence K description binding site for residue GOL B 203 source : AC7 12) chain B residue 71 type sequence I description binding site for residue GOL B 203 source : AC7 13) chain B residue 87 type sequence N description binding site for residue GOL B 203 source : AC7 14) chain B residue 140 type sequence A description binding site for residue GOL B 203 source : AC7 15) chain B residue 35 type SITE sequence D description Cleavage; by CASP3 => ECO:0000269|PubMed:37993714, ECO:0000269|PubMed:9334240 source Swiss-Prot : SWS_FT_FI1

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