eF-site ID 4xeg-A PDB Code 4xeg Chain A click to enlarge Title Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch Classification HYDROLASE/DNA Compound G/T mismatch-specific thymine DNA glycosylase Source (4XEG) Sequence A:  FNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGH HYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFT NMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFN GKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMP SSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNM Description Functional site 1) chain A residue 131 type sequence N description binding site for residue EDO A 401 source : AC1 2) chain A residue 132 type sequence L description binding site for residue EDO A 401 source : AC1 3) chain A residue 223 type sequence Q description binding site for residue EDO A 401 source : AC1 4) chain A residue 225 type sequence R description binding site for residue EDO A 401 source : AC1 5) chain A residue 287 type sequence H description binding site for residue EDO A 402 source : AC2 6) chain A residue 138 type sequence G description binding site for residue ACY A 403 source : AC3 7) chain A residue 139 type sequence I description binding site for residue ACY A 403 source : AC3 8) chain A residue 140 type sequence N description binding site for residue ACY A 403 source : AC3 9) chain A residue 152 type sequence Y description binding site for residue ACY A 403 source : AC3 10) chain A residue 191 type sequence N description binding site for residue ACY A 403 source : AC3 11) chain A residue 170 type sequence E description binding site for residue ACY A 404 source : AC4 12) chain A residue 184 type sequence K description binding site for residue ACY A 404 source : AC4 13) chain A residue 185 type sequence Y description binding site for residue ACY A 404 source : AC4 14) chain A residue 249 type sequence N description binding site for residue ACY A 405 source : AC5 15) chain A residue 256 type sequence P description binding site for residue ACY A 405 source : AC5 16) chain A residue 140 type sequence N description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 17) chain A residue 157 type sequence N description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 18) chain A residue 199 type sequence G description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 19) chain A residue 200 type sequence S description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 20) chain A residue 201 type sequence K description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 21) chain A residue 271 type sequence S description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 22) chain A residue 273 type sequence S description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 23) chain A residue 274 type sequence A description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 24) chain A residue 275 type sequence R description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 25) chain A residue 276 type sequence C description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 26) chain A residue 277 type sequence A description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 27) chain A residue 278 type sequence Q description binding site for Poly-Saccharide residues DA D 16 through DG D 18 source : AC6 28) chain A residue 140 type catalytic sequence N description 834 source MCSA : MCSA1 29) chain A residue 151 type catalytic sequence H description 834 source MCSA : MCSA1 30) chain A residue 248 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI1

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