eF-site ID 4xbj-D PDB Code 4xbj Chain D click to enlarge Title Y274F alanine racemase from E. coli inhibited by l-ala-p Classification ISOMERASE/ISOMERASE INHIBITOR Compound Alanine racemase, biosynthetic Source Escherichia coli (strain K12) (ALR1_ECOLI) Sequence D:  ATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLL ETARTLPADAFGVARLEEALRLRAGGITKPVLLLEGFFDA RDLPTISAQHFHTAVHNEEQLAALEEASDEPVTVWMKLDT GMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADE PCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFD WVRPGIILYGVSPLRSTGADFGCQPVMSLTSSLIAVREHK AGEPVGYGGTWVSERDTRLGVVAMGFGDGYPRAAPSGTPV LVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEG LPVERIAEMTKVSAYELITRLTSRVAMKYVD Description Functional site 1) chain D residue 255 type sequence Y description binding site for residue IN5 C 401 source : AC7 2) chain D residue 302 type sequence A description binding site for residue IN5 C 401 source : AC7 3) chain D residue 303 type sequence M description binding site for residue IN5 C 401 source : AC7 4) chain D residue 304 type sequence D description binding site for residue IN5 C 401 source : AC7 5) chain D residue 266 type sequence R description binding site for residue SO4 C 404 source : AD1 6) chain D residue 317 type sequence K description binding site for residue SO4 C 404 source : AD1 7) chain D residue 38 type sequence Y description binding site for residue SO4 D 401 source : AD2 8) chain D residue 193 type sequence A description binding site for residue SO4 D 401 source : AD2 9) chain D residue 194 type sequence S description binding site for residue SO4 D 401 source : AD2 10) chain D residue 211 type sequence G description binding site for residue SO4 D 401 source : AD2 11) chain D residue 212 type sequence I description binding site for residue SO4 D 401 source : AD2 12) chain D residue 343 type sequence Y description binding site for residue SO4 D 401 source : AD2 13) chain D residue 34 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:18434499 source Swiss-Prot : SWS_FT_FI4 14) chain D residue 34 type ACT_SITE sequence K description Proton acceptor; specific for D-alanine => ECO:0000255|HAMAP-Rule:MF_01201 source Swiss-Prot : SWS_FT_FI1 15) chain D residue 122 type MOD_RES sequence K description N6-carboxylysine => ECO:0000269|PubMed:18434499 source Swiss-Prot : SWS_FT_FI5 16) chain D residue 129 type BINDING sequence R description BINDING => ECO:0000305|PubMed:18434499 source Swiss-Prot : SWS_FT_FI3 17) chain D residue 303 type BINDING sequence M description BINDING => ECO:0000305|PubMed:18434499 source Swiss-Prot : SWS_FT_FI3 18) chain D residue 255 type ACT_SITE sequence Y description Proton acceptor; specific for L-alanine => ECO:0000255|HAMAP-Rule:MF_01201 source Swiss-Prot : SWS_FT_FI2

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