|
|
eF-site ID
|
4x8t-L |
|
PDB Code
|
4x8t |
|
Chain
|
L |
|
click to enlarge
|
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Title
|
FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-chloro-3,4-dihydroisoquinolin-1(2H)-one |
|
Classification
|
hydrolase/hydrolase inhibitor |
|
Compound
|
Factor VIIa (Heavy Chain) |
|
Source
|
Homo sapiens (Human) (FA7_HUMAN) |
|
|
Sequence
|
L: |
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTP
TVEYPCGKIPILEKR
|
|
|
Description
|
(1) |
Factor VIIa (Heavy Chain) (E.C.3.4.21.21), Factor VIIa (Light Chain) (E.C.3.4.21.21)
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
115 |
| type |
|
| sequence |
H
|
| description |
binding site for residue SO4 H 305
|
| source |
: AC5
|
|
|
2)
|
chain |
L |
| residue |
116 |
| type |
|
| sequence |
E
|
| description |
binding site for residue SO4 H 305
|
| source |
: AC5
|
|
|
3)
|
chain |
L |
| residue |
112-127 |
| type |
prosite |
| sequence |
CRCHEGYSLLADGVSC
|
| description |
EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC
|
| source |
prosite : PS01186
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