|
eF-site ID
|
4x8m-A |
PDB Code
|
4x8m |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Crystal structure of E. coli Adenylate kinase Y171W mutant |
Classification
|
TRANSFERASE |
Compound
|
Adenylate kinase |
Source
|
Escherichia coli (strain K12) (KAD_ECOLI) |
|
Sequence
|
A: |
MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVK
SGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNG
FLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRI
VGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
EETVRKRLVEWHQMTAPLIGYYSKEAEAGNTKYAKVDGTK
PVAEVRADLEKILG
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
119 |
type |
BINDING |
sequence |
R
|
description |
BINDING => ECO:0000269|PubMed:16302237
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
2)
|
chain |
A |
residue |
192 |
type |
MOD_RES |
sequence |
K
|
description |
N6-acetyllysine => ECO:0000269|PubMed:18723842
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
3)
|
chain |
A |
residue |
10 |
type |
BINDING |
sequence |
G
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
4)
|
chain |
A |
residue |
31 |
type |
BINDING |
sequence |
T
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
5)
|
chain |
A |
residue |
36 |
type |
BINDING |
sequence |
R
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
6)
|
chain |
A |
residue |
57 |
type |
BINDING |
sequence |
K
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
7)
|
chain |
A |
residue |
92 |
type |
BINDING |
sequence |
Q
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
8)
|
chain |
A |
residue |
123 |
type |
BINDING |
sequence |
R
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
9)
|
chain |
A |
residue |
156 |
type |
BINDING |
sequence |
R
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
10)
|
chain |
A |
residue |
200 |
type |
BINDING |
sequence |
K
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:7937733, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
11)
|
chain |
A |
residue |
85 |
type |
BINDING |
sequence |
G
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
12)
|
chain |
A |
residue |
167 |
type |
BINDING |
sequence |
R
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
13)
|
chain |
A |
residue |
81-92 |
type |
prosite |
sequence |
FLLDGFPRTIPQ
|
description |
ADENYLATE_KINASE Adenylate kinase signature. FLLDGFPRtipQ
|
source |
prosite : PS00113
|
|
14)
|
chain |
A |
residue |
132 |
type |
BINDING |
sequence |
V
|
description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00235, ECO:0000269|PubMed:1548697, ECO:0000269|PubMed:16302237, ECO:0000269|PubMed:19805185, ECO:0000269|PubMed:8451239
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|