eF-site ID 4wqt-D PDB Code 4wqt Chain D click to enlarge Title Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) Classification TRANSFERASE/TRANSCRIPTION Compound DNA-directed RNA polymerase subunit alpha Source ORGANISM_SCIENTIFIC: Thermus thermophilus HB8; Sequence D:  MKKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPE RDGLFDERIFGPIKDRRYRMGHIELATPAAHIWFVKDVPS KIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKR QLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQE LAPGVVSRLDGVALYRFPRRVRVEYVPKDYRVQPHMNVVV PEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILV VKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRV EVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEK ELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILE AVPVLPPDLRATSDLNDLYRRLINRNNRLKKLLAQGAPEI IIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTD ILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLP KRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKD EVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQS IQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLS AHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLE FATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFAN PDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARI VAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGME KTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLE EADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQ AVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLM QKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTA LRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQP DEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRY LSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCY GYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGG VAGAADITQGLPRVIELFEARRPKAKAVISEIDGVVRIEE TEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPL TRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHD KHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNE RLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTH VLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQ VVDQKTLKAIEEAR Description Functional site 1) chain D residue 1112 type sequence C description binding site for residue ZN D 2001 source : AC1 2) chain D residue 1194 type sequence C description binding site for residue ZN D 2001 source : AC1 3) chain D residue 1200 type sequence V description binding site for residue ZN D 2001 source : AC1 4) chain D residue 1201 type sequence C description binding site for residue ZN D 2001 source : AC1 5) chain D residue 1204 type sequence C description binding site for residue ZN D 2001 source : AC1 6) chain D residue 739 type sequence D description binding site for residue MG D 2002 source : AC2 7) chain D residue 741 type sequence D description binding site for residue MG D 2002 source : AC2 8) chain D residue 743 type sequence D description binding site for residue MG D 2002 source : AC2 9) chain D residue 1201 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16298991 source Swiss-Prot : SWS_FT_FI1 10) chain D residue 1204 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16298991 source Swiss-Prot : SWS_FT_FI1 11) chain D residue 743 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16298991 source Swiss-Prot : SWS_FT_FI1 12) chain D residue 1112 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16298991 source Swiss-Prot : SWS_FT_FI1 13) chain D residue 1194 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16298991 source Swiss-Prot : SWS_FT_FI1

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