eF-site ID 4wns-B PDB Code 4wns Chain B click to enlarge Title Crystal structure of Transthyretin complexed with pterostilbene Classification TRANSPORT PROTEIN Compound Transthyretin Source Homo sapiens (Human) (TTHY_HUMAN) Sequence B:  CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKT SESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHE HAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN Description Functional site 1) chain B residue 41 type sequence W description binding site for residue SO4 A 201 source : AC1 2) chain B residue 70 type sequence K description binding site for residue SO4 A 201 source : AC1 3) chain B residue 70 type sequence K description binding site for residue SO4 B 201 source : AC3 4) chain B residue 72 type sequence E description binding site for residue SO4 B 201 source : AC3 5) chain B residue 90 type sequence H description binding site for residue SO4 B 201 source : AC3 6) chain B residue 92 type sequence E description binding site for residue SO4 B 201 source : AC3 7) chain B residue 26 type sequence I description binding site for residue DMS B 202 source : AC4 8) chain B residue 27 type sequence N description binding site for residue DMS B 202 source : AC4 9) chain B residue 78 type sequence Y description binding site for residue DMS B 202 source : AC4 10) chain B residue 64 type sequence F description binding site for residue DMS B 203 source : AC5 11) chain B residue 98 type sequence N description binding site for residue DMS B 203 source : AC5 12) chain B residue 99 type sequence D description binding site for residue DMS B 203 source : AC5 13) chain B residue 102 type sequence P description binding site for residue DMS B 203 source : AC5 14) chain B residue 105 type sequence Y description binding site for residue DMS B 203 source : AC5 15) chain B residue 15 type sequence K description binding site for residue 3RL B 204 source : AC6 16) chain B residue 17 type sequence L description binding site for residue 3RL B 204 source : AC6 17) chain B residue 110 type sequence L description binding site for residue 3RL B 204 source : AC6 18) chain B residue 110 type sequence L description binding site for residue 3RL B 204 source : AC6 19) chain B residue 117 type sequence S description binding site for residue 3RL B 204 source : AC6 20) chain B residue 117 type sequence S description binding site for residue 3RL B 204 source : AC6 21) chain B residue 98 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 source Swiss-Prot : SWS_FT_FI5 22) chain B residue 15 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 23) chain B residue 54 type BINDING sequence E description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 24) chain B residue 117 type BINDING sequence S description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 25) chain B residue 10 type MOD_RES sequence C description Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E source Swiss-Prot : SWS_FT_FI2 26) chain B residue 42 type MOD_RES sequence E description 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 source Swiss-Prot : SWS_FT_FI3 27) chain B residue 52 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P02767 source Swiss-Prot : SWS_FT_FI4

Display surface Download Links