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eF-site ID
|
4wk8-ABFG |
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PDB Code
|
4wk8 |
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Chain
|
A, B, F, G |
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click to enlarge
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Title
|
FOXP3 forms a domain-swapped dimer to bridge DNA |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3') |
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Source
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(FOXP3_HUMAN) |
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Sequence
|
A: |
TTAGGAAAATTTGTTTCATAG
|
| B: |
AACTATGAAACAAATTTTCCT
|
| F: |
RPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRN
HPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKK
|
| G: |
RPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRN
HPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKK
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
F |
| residue |
381-387 |
| type |
prosite |
| sequence |
WKNAIRH
|
| description |
FORK_HEAD_2 Fork head domain signature 2. WKNAIRH
|
| source |
prosite : PS00658
|
|
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2)
|
chain |
G |
| residue |
393 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q99JB6
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
F |
| residue |
393 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q99JB6
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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