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eF-site ID
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4wk0-B |
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PDB Code
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4wk0 |
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Chain
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B |
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click to enlarge
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Title
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Metal Ion and Ligand Binding of Integrin |
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Classification
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CELL ADHESION/IMMUNE SYSTEM |
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Compound
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Integrin alpha-5 |
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Source
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(4WK0) |
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Sequence
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B: |
NRCLKANAKSCGECIQAGPNCGWCTNSTFLTSARCDDLEA
LKKKGCPPDDIENPRGSKDIKKNKNVTNLKPEDITQIQPQ
QLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKD
DLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYIS
TTPAKLRNPCTSEQNCTTPFSYKNVLSLTNKGEVFNELVG
KQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFS
TDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYP
SIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAV
GTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISY
KSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPK
KDSDSFKIRPLGFTEEVEVILQYICEC
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Description
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Functional site
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1)
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chain |
B |
| residue |
224 |
| type |
BINDING |
| sequence |
N
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI5
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2)
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chain |
B |
| residue |
226 |
| type |
BINDING |
| sequence |
D
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| description |
in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI5
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3)
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chain |
B |
| residue |
228 |
| type |
BINDING |
| sequence |
P
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| description |
in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI5
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4)
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chain |
B |
| residue |
30 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI6
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5)
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chain |
B |
| residue |
74 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI6
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6)
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chain |
B |
| residue |
77 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI6
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7)
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chain |
B |
| residue |
192 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
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| source |
Swiss-Prot : SWS_FT_FI7
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8)
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chain |
B |
| residue |
249 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI8
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9)
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chain |
B |
| residue |
343 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33962943, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI9
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10)
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chain |
B |
| residue |
397 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33962943, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI9
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11)
|
chain |
B |
| residue |
386 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI10
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12)
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chain |
B |
| residue |
132 |
| type |
BINDING |
| sequence |
S
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| description |
in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI1
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13)
|
chain |
B |
| residue |
229 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI1
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14)
|
chain |
B |
| residue |
134 |
| type |
BINDING |
| sequence |
S
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| description |
in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI4
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| source |
Swiss-Prot : SWS_FT_FI2
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15)
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chain |
B |
| residue |
137 |
| type |
BINDING |
| sequence |
D
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| description |
in ADMIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI3
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16)
|
chain |
B |
| residue |
138 |
| type |
BINDING |
| sequence |
D
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| description |
in ADMIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI3
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17)
|
chain |
B |
| residue |
342 |
| type |
BINDING |
| sequence |
A
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| description |
in ADMIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:7NXD
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| source |
Swiss-Prot : SWS_FT_FI3
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18)
|
chain |
B |
| residue |
169 |
| type |
BINDING |
| sequence |
E
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4
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| source |
Swiss-Prot : SWS_FT_FI4
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