eF-site ID 4wfr-A PDB Code 4wfr Chain A click to enlarge Title Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A, complexed with 2'-AMP Classification HYDROLASE Compound 2',3'-cyclic-nucleotide 3'-phosphodiesterase Source Mus musculus (Mouse) (CN37_MOUSE) Sequence A:  KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKE LRHFISEKLELVSYFGKRPPGVLHCATKFCDYGKAAGAEE YAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQEL QLWPSDSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDI LQQVKGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFT GYYG Description Functional site 1) chain A residue 168 type sequence Y description binding site for residue 2AM A 401 source : AC1 2) chain A residue 230 type sequence H description binding site for residue 2AM A 401 source : AC1 3) chain A residue 235 type sequence F description binding site for residue 2AM A 401 source : AC1 4) chain A residue 309 type sequence H description binding site for residue 2AM A 401 source : AC1 5) chain A residue 311 type sequence T description binding site for residue 2AM A 401 source : AC1 6) chain A residue 320 type sequence P description binding site for residue 2AM A 401 source : AC1 7) chain A residue 321 type sequence V description binding site for residue 2AM A 401 source : AC1 8) chain A residue 230 type ACT_SITE sequence H description Proton acceptor => ECO:0000269|PubMed:22393399 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 309 type ACT_SITE sequence H description Proton donor => ECO:0000269|PubMed:22393399 source Swiss-Prot : SWS_FT_FI2 10) chain A residue 232 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI3 11) chain A residue 311 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 12) chain A residue 207 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13233 source Swiss-Prot : SWS_FT_FI4 13) chain A residue 219 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13233 source Swiss-Prot : SWS_FT_FI4

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