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eF-site ID
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4wf4-A |
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PDB Code
|
4wf4 |
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Chain
|
A |
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click to enlarge
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Title
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Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4 |
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Classification
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OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
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Compound
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Thiol:disulfide interchange protein |
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Source
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ORGANISM_SCIENTIFIC: Escherichia coli BL21(DE3); |
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Sequence
|
A: |
AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVL
HISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAM
ALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGE
EYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQ
LNPQGMDTSNMDVFVQQYADTVKYLSEK
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
147 |
| type |
|
| sequence |
L
|
| description |
binding site for residue EDO A 201
|
| source |
: AC1
|
|
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2)
|
chain |
A |
| residue |
147 |
| type |
|
| sequence |
L
|
| description |
binding site for residue EDO A 201
|
| source |
: AC1
|
|
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3)
|
chain |
A |
| residue |
148 |
| type |
|
| sequence |
R
|
| description |
binding site for residue EDO A 201
|
| source |
: AC1
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|
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4)
|
chain |
A |
| residue |
65 |
| type |
|
| sequence |
G
|
| description |
binding site for residue WF4 B 201
|
| source |
: AC2
|
|
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5)
|
chain |
A |
| residue |
68 |
| type |
|
| sequence |
L
|
| description |
binding site for residue WF4 B 201
|
| source |
: AC2
|
|
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6)
|
chain |
A |
| residue |
22-40 |
| type |
prosite |
| sequence |
VLEFFSFFCPHCYQFEEVL
|
| description |
THIOREDOXIN_1 Thioredoxin family active site. VLeFFsfFCPHCYqFeevL
|
| source |
prosite : PS00194
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