eF-site ID 4vgc-ABC PDB Code 4vgc Chain A, B, C click to enlarge Title GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX Classification SERINE PROTEASE Compound GAMMA CHYMOTRYPSIN Source ORGANISM_COMMON: cattle; ORGANISM_SCIENTIFIC: Bos taurus; Sequence A:  CGVPAIQPVL B:  IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTA AHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYN SLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT CVTTGWGLTRY C:  TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSS CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYAR VTALVNWVQQTLAAN Description Functional site 1) chain B residue 57 type sequence H description THE CATALYTIC SITE WHICH INCLUDES THE INHIBITOR PATCHED TO SERINE 195 AND HISTIDINE 57. source : CAT 2) chain B residue 102 type sequence D description THE CATALYTIC SITE WHICH INCLUDES THE INHIBITOR PATCHED TO SERINE 195 AND HISTIDINE 57. source : CAT 3) chain C residue 195 type sequence S description THE CATALYTIC SITE WHICH INCLUDES THE INHIBITOR PATCHED TO SERINE 195 AND HISTIDINE 57. source : CAT 4) chain C residue 153 type sequence D description BINDING SITE FOR RESIDUE SO4 C 357 source : AC1 5) chain C residue 154 type sequence R description BINDING SITE FOR RESIDUE SO4 C 357 source : AC1 6) chain C residue 156 type sequence Q description BINDING SITE FOR RESIDUE SO4 C 357 source : AC1 7) chain B residue 36 type sequence K description BINDING SITE FOR RESIDUE SO4 B 358 source : AC2 8) chain B residue 92 type sequence S description BINDING SITE FOR RESIDUE SO4 B 358 source : AC2 9) chain C residue 237 type sequence W description BINDING SITE FOR RESIDUE SO4 B 358 source : AC2 10) chain B residue 57 type sequence H description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 11) chain C residue 190 type sequence S description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 12) chain C residue 192 type sequence M description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 13) chain C residue 195 type sequence S description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 14) chain C residue 213 type sequence V description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 15) chain C residue 214 type sequence S description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 16) chain C residue 215 type sequence W description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 17) chain C residue 216 type sequence G description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 18) chain C residue 217 type sequence S description BINDING SITE FOR RESIDUE SRD C 358 source : AC3 19) chain C residue 193 type catalytic sequence G description 387 source MCSA : MCSA1 20) chain C residue 195 type catalytic sequence S description 387 source MCSA : MCSA1 21) chain C residue 196 type catalytic sequence G description 387 source MCSA : MCSA1 22) chain B residue 53-58 type prosite sequence VTAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC source prosite : PS00134 23) chain C residue 189-200 type prosite sequence SSCMGDSGGPLV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV source prosite : PS00135 24) chain C residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 25) chain B residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1

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