|
|
eF-site ID
|
4v8o-.AA.AV.AX.BA.BB |
|
PDB Code
|
4v8o |
|
Chain
|
AA, AV, AX, BA, BB |
|
|
|
|
Title
|
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 |
|
Classification
|
RIBOSOME |
|
Compound
|
16S RRNA |
|
Source
|
ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS; |
|
|
Sequence
|
AA: |
UGGAGAGUUUGAUCCUGGCUCAGGGUGAACGCUGGCGGCG
UGCCUAAGACAUGCAAGUCGUGCGGGCCGCGGGGUUUUAC
UCCGUGGUCAGCGGCGGACGGGUGAGUAACGCGUGGGUGA
CCUACCCGGAAGAGGGGGACAACCCGGGGAAACUCGGGCU
AAUCCCCCAUGUGGACCCGCCCCUUGGGGUGUGUCCAAAG
GGCUUUGCCCGCUUCCGGAUGGGCCCGCGUCCCAUCAGCU
AGUUGGUGGGGUAAUGGCCCACCAAGGCGACGACGGGUAG
CCGGUCUGAGAGGAUGGCCGGCCACAGGGGCACUGAGACA
CGGGCCCCACUCCUACGGGAGGCAGCAGUUAGGAAUCUUC
CGCAAUGGGCGCAAGCCUGACGGAGCGACGCCGCUUGGAG
GAAGAAGCCCUUCGGGGUGUAAACUCCUGAACCCGGGACG
AAACCCCCGACGAGGGGACUGACGGUACCGGGGUAAUAGC
GCCGGCCAACUCCGUGCCAGCAGCCGCGGUAAUACGGAGG
GCGCGAGCGUUACCCGGAUUCACUGGGCGUAAAGGGCGUG
UAGGCGGCCUGGGGCGUCCCAUGUGAAAGACCACGGCUCA
ACCGUGGGGGAGCGUGGGAUACGCUCAGGCUAGACGGUGG
GAGAGGGUGGUGGAAUUCCCGGAGUAGCGGUGAAAUGCGC
AGAUACCGGGAGGAACGCCGAUGGCGAAGGCAGCCACCUG
GUCCACCCGUGACGCUGAGGCGCGAAAGCGUGGGGAGCAA
ACCGGAUUAGAUACCCGGGUAGUCCACGCCCUAAACGAUG
CGCGCUAGGUCUCUGGGUCUCCUGGGGGCCGAAGCUAACG
CGUUAAGCGCGCCGCCUGGGGAGUACGGCCGCAAGGCUGA
AACUCAAAGGAAUUGACGGGGGCCCGCACAAGCGGUGGAG
CAUGUGGUUUAAUUCGAAGCAACGCGAAGAACCUUACCAG
GCCUUGACAUGCUAGGGAACCCGGGUGAAAGCCUGGGGUG
CCCCGCGAGGGGAGCCCUAGCACAGGUGCUGCAUGGCCGU
CGUCAGCUCGUGCCGUGAGGUGUUGGGUUAAGUCCCGCAA
CGAGCGCAACCCCCGCCGUUAGUUGCCAGCGGUUCGGCCG
GGCACUCUAACGGGACUGCCCGCGAAAGCGGGAGGAAGGA
GGGGACGACGUCUGGUCAGCAUGGCCCUUACGGCCUGGGC
GACACACGUGCUACAAUGCCCACUACAAAGCGAUGCCACC
CGGCAACGGGGAGCUAAUCGCAAAAAGGUGGGCCCAGUUC
GGAUUGGGGUCUGCAACCCGACCCCAUGAAGCCGGAAUCG
CUAGUAAUCGCGGAUCAGCCAUGCCGCGGUGAAUACGUUC
CCGGGCCUUGUACACACCGCCCGUCACGCCAUGGGAGCGG
GCUCUACCCGAAGUCGCCGGGAGCCUACGGGCAGGCGCCG
AGGGUAGGGCCCGUGACUGGGGCGAAGUCGUAACAAGGUA
GCUGUACCGGAAGGUGCGGCUGGA
|
| AV: |
CGCGGGGUGGAGCAGCCUGGUAGCUCGUCGGGCUCAUAAC
CCGAAGGUCGUCGGUUCAAAUCCGGCCCCCGCAACCA
|
| AX: |
AAAAAAUGU
|
| BA: |
AGAUGGUAAGGGCCCACGGUGGAUGCCUCGGCACCCGAGC
CGAUGAAGGACGUGGCUACCUGCGAUAAGCCAGGGGGAGC
CGGUAGCGGGCGUGGAUCCCUGGAUGUCCGAAUGGGGGAA
CCCGGCCGGCGGGAACGCCGGUCACCGCGCUUUUGCGCGG
GGGGAACCUGGGGAACUGAAACAUCUCAGUACCCAGAGGA
GAGGAAAGAGAAAUCGACUCCCUGAGUAGCGGCGAGCGAA
AGGGGACCAGCCUAAACCGUCCGGCUUGUCCGGGCGGGGU
CGUGGGGCCCUCGGACACCGAAUCCCCAGCCUAGCCGAAG
CUGUUGGGAAGCAGCGCCAGAGAGGGUGAAAGCCCCGUAG
GCGAAAGGUGGGGGGAUAGGUGAGGGUACCCGAGUACCCC
GUGGUUCGUGGAGCCAUGGGGGAAUCUGGGCGGACCACCG
CCUAAGGCUAAGUACUCCGGGUGACCGAUAGCGCACCAGU
ACCGUGAGGGAAAGGUGAAAAGAACCCCGGGAGGGGAGUG
AAAUAGAGCCUGAAACCGUGGGCUUACAAGCAGUCACGGC
CCCGCAAGGGGUUGUGGCGUGCCUAUUGAAGCAUGAGCCG
GCGACUCACGGUCGUGGGCGAGCUUAAGCCGUUGAGGCGG
AGGCGUAGGGAAACCGAGUCCGAACAGGGCGCAAGCGGGC
CGCACGCGGCCCGCAAAGUCCGCGGCCGUGGACCCGAAAC
CGGGCGAGCUAGCCCUGGCCAGGGUGAAGCUGGGGUGAGA
CCCAGUGGAGGCCCGAACCGGUGGGGGAUGCAAACCCCUC
GGAUGAGCUGGGGCUAGGAGUGAAAAGCUAACCGAGCCCG
GAGAUAGCUGGUUCUCCCCGAAAUGACUUUAGGGUCAGCC
UCAGGCGCUGACUGGGGCCUGUAGAGCACUGAUAGGGCUA
GGGGGCCCACCAGCCUACCAAACCCUGUCAAACUCCGAAG
GGUCCCAGGUGGAGCCUGGGAGUGAGGGCGCGAGCGAUAA
CGUCCGCGUCCGAGCGCGGGAACAACCGAGACCGCCAGCU
AAGGCCCCCAAGUCUGGGCUAAGUGGUAAAGGAUGUGGCG
CGGCGAAGACAGCCAGGAGGUUGGCUUAGAAGCAGCCAUC
CUUUAAAGAGUGCGUAAUAGCUCACUGGUCGAGUGGCGCC
GCGCCGAAAAUGAUCGGGGCUUAAGCCCAGCGCCGAAGCU
GCGGGUCUGGGGGAUGACCCCAGGCGGUAGGGGAGCGUUC
CCGAUGCCGAUGAAGGCCGACCCGCGAGGGCGGCUGGAGG
UAAGGGAAGUGCGAAUGCCGGCAUGAGUAACGAUAAAGAG
GGUGAGAAUCCCUCUCGCCGUAAGCCCAAGGGUUCCUACG
CAAUGGUCGUCAGCGUAGGGUUAGGCGGGACCUAAGGUGA
AGCCGAAAGGCGUAGCCGAAGGGCAGCCGGUUAAUAUUCC
GGCCCUUCCCGCAGGUGCGAUGGGGGGACGCUCUAGGCUA
GGGGGACCGGAGCCAUGGACGAGCCCGGCCAGAAGCGCAG
GGUGGGAGGUAGGCAAAUCCGCCUCCCAACAAGCUCUGCG
UGGUGGGGAAGCCCGUACGGGUGACAACCCCCCGAAGCCA
GGGAGCCAAGAAAAGCCUCUAAGCACAACCUGCGGGAACC
CGUACCGCAAACCGACACAGGUGGGCGGGUGCAAGAGCAC
UCAGGCGCGCGGGAGAACCCUCGCCAAGGAACUCUGCAAG
UUGGCCCCGUAACUUCGGGAGAAGGGGUGCUCCCUGGGGU
GAUGAGCCCCGGGGAGCCGCAGUGAACAGGCUCUGGCGAC
UGUUUACCAAAAACACAGCUCUCUGCGAACUCGUAAGAGG
AGGUAUAGGGAGCGACGCUUGCCCGGUGCCGGAAGGUCAA
GGGGAGGGGUGCAAGCCCCGAACCGAAGCCCCGGUGAACG
GCGGCCGUAACUAUAACGGUCCUAAGGUAGCGAAAUUCCU
UGUCGGGUAAGUUCCGACCUGCACGAAAAGCGUAACGACC
GGAGCGCUGUCUCGGCGAGGGACCCGGUGAAAUUGAACUG
GCCGUGAAGAUGCGGCCUACCCGUGGCAGGACGAAAAGAC
CCCGUGGAGCUUUACUGCAGCCUGGUGUUGGCUCUUGGUC
GCGCCUGCGUAGGAUAGGUGGGAGCCUGUGAACCCCCGCC
UCCGGGUGGGGGGGAGGCGCCGGUGAAAUACCACCCUGGC
GCGGCUGGGGGCCUAACCCUCGGAUGGGGGGACAGCGCUU
GGCGGGCAGUUUGACUGGGGCGGUCGCCUCCUAAAAGGUA
ACGGAGGCGCCCAAAGGUCCCCUCAGGCGGGACGGAAAUC
CGCCGGAGAGCGCAAGGGUAGAAGGGGGCCUGACUGCGAG
GCCUGCAAGCCGAGCAGGGGCGAAAGCCGGGCCUAGUGAA
CCGGUGGUCCCGUGUGGAAGGGCCAUCGAUCAACGGAUAA
AAGUUACCCCGGGGAUAACAGGCUGAUCUCCCCCGAGCGU
CCACAGCGGCGGGGAGGUUUGGCACCUCGAUGUCGGCUCG
UCGCAUCCUGGGGCUGAAGAAGGUCCCAAGGGUUGGGCUG
UUCGCCCAUUAAAGCGGCACGCGAGCUGGGUUCAGAACGU
CGUGAGACAGUUCGGUCUCUAUCCGCCACGGGCGCAGGAG
GCUUGAGGGGGGCUCUUCCUAGUACGAGAGGACCGGAAGG
GACGCACCUCUGGUUUCCCAGCUGUCCCUCCAGGGGCAUA
AGCUGGGUAGCCAUGUGCGGAAGGGAUAACCGCUGAAAGC
AUCUAAGCGGGAAGCCCGCCCCAAGAUGAGGCCUCCCACG
GCGUCAAGCCGGUAAGGACCCGGGAAGACCACCCGGUGGA
UGGGCCGGGGGUGUAAGCGCCGCGAGGCGUUGAGCCGACC
GGUCCCAAUCGUCCGAGGUCU
|
| BB: |
UCCCCCGUGCCCAUAGCGGCGUGGAACCACCCGUUCCCAU
UCCGAACACGGAAGUGAAACGCGCCAGCGCCGAUGGUACU
GGGCGGGCGACCGCCUGGGAGAGUAGGUCGGUGCGGGGG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
BA |
| residue |
2655 |
| type |
|
| sequence |
G
|
| description |
binding site for residue GCP AY 1000
|
| source |
: AC1
|
|
|
2)
|
chain |
BA |
| residue |
2656 |
| type |
|
| sequence |
U
|
| description |
binding site for residue GCP AY 1000
|
| source |
: AC1
|
|
|
|