eF-site ID 4uy4-BD
PDB Code 4uy4
Chain B, D

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Title 1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
Classification PEPTIDE BINDING PROTEIN
Compound SPINDLIN-4
Source (4UY4)
Sequence B:  SMTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTL
YIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSR
LADSLIGKAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFY
ITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQED
SLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDI
HIYVYGLV
D:  ARTXQT
Description


Functional site

1) chain D
residue 3
type MOD_RES
sequence T
description Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088
source Swiss-Prot : SWS_FT_FI2

2) chain D
residue 4
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI3

3) chain D
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
source Swiss-Prot : SWS_FT_FI4

4) chain D
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790
source Swiss-Prot : SWS_FT_FI5

5) chain D
residue 2
type MOD_RES
sequence R
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1

6) chain B
residue 159
type MOD_RES
sequence D
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1

7) chain B
residue 170
type MOD_RES
sequence D
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1


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