eF-site ID 4uy4-AC
PDB Code 4uy4
Chain A, C

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Title 1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
Classification PEPTIDE BINDING PROTEIN
Compound SPINDLIN-4
Source (4UY4)
Sequence A:  SMTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTL
YIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSR
LADSLIGKAVEHVFETKDEWKGMVLARAPVMDTWFYITYE
KDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQESLVGK
QVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVY
GLV
C:  ARTXQT
Description


Functional site

1) chain A
residue 65
type
sequence E
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

2) chain A
residue 67
type
sequence V
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

3) chain A
residue 149
type
sequence Y
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

4) chain A
residue 210
type
sequence I
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

5) chain A
residue 211
type
sequence H
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

6) chain A
residue 221
type
sequence F
description BINDING SITE FOR RESIDUE GOL A 1237
source : AC1

7) chain C
residue 3
type MOD_RES
sequence T
description Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088
source Swiss-Prot : SWS_FT_FI2

8) chain C
residue 4
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI3

9) chain C
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
source Swiss-Prot : SWS_FT_FI4

10) chain C
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790
source Swiss-Prot : SWS_FT_FI5

11) chain C
residue 2
type MOD_RES
sequence R
description Citrulline; alternate => ECO:0000269|PubMed:16567635
source Swiss-Prot : SWS_FT_FI1


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