eF-site ID 4uxd-D PDB Code 4uxd Chain D click to enlarge Title 2-keto 3-deoxygluconate aldolase from Picrophilus torridus Classification LYASE Compound 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE Source (KDGA_PICTO) Sequence D:  MYKGIVCPMITPLDAHGNIDYNATNILIKYLEGINVDYLF PMGSTGVFPYFTLKERKDFLKFVRENSKKPIMAGVGSSSI NEVNELMKFSMDIGIEAAVLMPPYYIKLNQEAIYHYYKEI LSSNDMDLLIYNIPQFTNKIDPETVKNLKSEFSSVKGVKD SSADIRGFMEMLSLSDDDFAVFQGQDDLLFTSLELGASGG VCGTTNFSDGIVRLYHEYKNNREMALKIEKNDVIPLMKKL GKYQFPNAYYEYFYKKNNINGGYRPPMYRVGIEI Description Functional site 1) chain D residue 8 type sequence P description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 2) chain D residue 40 type sequence F description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 3) chain D residue 43 type sequence G description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 4) chain D residue 44 type sequence S description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 5) chain D residue 45 type sequence T description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 6) chain D residue 131 type sequence Y description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 7) chain D residue 161 type sequence S description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 8) chain D residue 184 type sequence G description BINDING SITE FOR RESIDUE GOL D 1275 source : BC1 9) chain D residue 184 type sequence G description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 10) chain D residue 186 type sequence D description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 11) chain D residue 201 type sequence V description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 12) chain D residue 202 type sequence C description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 13) chain D residue 203 type sequence G description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 14) chain D residue 237 type sequence M description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 15) chain D residue 249 type sequence Y description BINDING SITE FOR RESIDUE EDO D 1276 source : BC2 16) chain D residue 161 type sequence S description BINDING SITE FOR RESIDUE GOL D 1277 source : BC3 17) chain D residue 185 type sequence Q description BINDING SITE FOR RESIDUE GOL D 1277 source : BC3 18) chain D residue 245 type sequence F description BINDING SITE FOR RESIDUE GOL D 1277 source : BC3 19) chain D residue 187 type sequence D description BINDING SITE FOR RESIDUE EDO D 1278 source : BC5 20) chain D residue 234 type sequence I description BINDING SITE FOR RESIDUE EDO D 1278 source : BC5 21) chain D residue 238 type sequence K description BINDING SITE FOR RESIDUE EDO D 1278 source : BC5 22) chain D residue 19 type sequence I description BINDING SITE FOR RESIDUE EDO D 1279 source : BC6 23) chain D residue 20 type sequence D description BINDING SITE FOR RESIDUE EDO D 1279 source : BC6 24) chain D residue 21 type sequence Y description BINDING SITE FOR RESIDUE EDO D 1279 source : BC6 25) chain D residue 22 type sequence N description BINDING SITE FOR RESIDUE EDO D 1279 source : BC6 26) chain D residue 16 type sequence H description BINDING SITE FOR RESIDUE GOL D 1280 source : BC7 27) chain D residue 17 type sequence G description BINDING SITE FOR RESIDUE GOL D 1280 source : BC7 28) chain D residue 18 type sequence N description BINDING SITE FOR RESIDUE GOL D 1280 source : BC7 29) chain D residue 264 type sequence R description BINDING SITE FOR RESIDUE GOL D 1280 source : BC7 30) chain D residue 107 type sequence K description BINDING SITE FOR RESIDUE GOL D 1281 source : CC3 31) chain D residue 109 type sequence N description BINDING SITE FOR RESIDUE GOL D 1281 source : CC3 32) chain D residue 110 type sequence Q description BINDING SITE FOR RESIDUE GOL D 1281 source : CC3 33) chain D residue 139 type sequence K description BINDING SITE FOR RESIDUE GOL D 1281 source : CC3 34) chain D residue 104 type sequence Y description BINDING SITE FOR RESIDUE GOL D 1282 source : CC7 35) chain D residue 105 type sequence Y description BINDING SITE FOR RESIDUE GOL D 1282 source : CC7 36) chain D residue 136 type sequence F description BINDING SITE FOR RESIDUE GOL D 1282 source : CC7 37) chain D residue 137 type sequence T description BINDING SITE FOR RESIDUE GOL D 1282 source : CC7 38) chain D residue 138 type sequence N description BINDING SITE FOR RESIDUE GOL D 1282 source : CC7 39) chain D residue 234 type sequence I description BINDING SITE FOR RESIDUE GOL A 1281 source : CC8 40) chain D residue 107 type sequence K description BINDING SITE FOR RESIDUE IPA D 1283 source : DC2 41) chain D residue 134 type sequence P description BINDING SITE FOR RESIDUE IPA D 1283 source : DC2 42) chain D residue 137 type sequence T description BINDING SITE FOR RESIDUE IPA D 1283 source : DC2 43) chain D residue 139 type sequence K description BINDING SITE FOR RESIDUE IPA D 1283 source : DC2 44) chain D residue 159 type ACT_SITE sequence K description Schiff-base intermediate with substrate => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 45) chain D residue 44 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 46) chain D residue 131 type BINDING sequence Y description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 47) chain D residue 159 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 48) chain D residue 131 type SITE sequence Y description Proton shuttle => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

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