eF-site ID 4uv9-AB
PDB Code 4uv9
Chain A, B

click to enlarge
Title LSD1(KDM1A)-CoREST in complex with 1-Ethyl-Tranylcypromine
Classification TRANSCRIPTION
Compound LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A
Source Homo sapiens (Human) (RCOR1_HUMAN)
Sequence A:  PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVF
LFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVH
RVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSG
LAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG
AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAV
PKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQ
ALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVN
LKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTAL
CKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILD
WHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG
YSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRST
SQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSA
VQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGE
LFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAI
LKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSG
NDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPAT
VHGALLSGLREAGRIADQFLGAMYTL
B:  RKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKR
QIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEE
QLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR
FNIDEVLQEWEAE
Description (1)  LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A (E.C.1.-.-.-), REST COREPRESSOR 1


Functional site

1) chain A
residue 285
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

2) chain A
residue 287
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

3) chain A
residue 288
type
ligand
sequence V
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

4) chain A
residue 289
type
ligand
sequence S
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

5) chain A
residue 307
type
ligand
sequence L
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

6) chain A
residue 308
type
ligand
sequence E
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

7) chain A
residue 309
type
ligand
sequence A
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

8) chain A
residue 310
type
ligand
sequence R
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

9) chain A
residue 314
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

10) chain A
residue 315
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

11) chain A
residue 316
type
ligand
sequence R
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

12) chain A
residue 329
type
ligand
sequence L
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

13) chain A
residue 330
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

14) chain A
residue 331
type
ligand
sequence A
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

15) chain A
residue 332
type
ligand
sequence M
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

16) chain A
residue 333
type
ligand
sequence V
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

17) chain A
residue 538
type
ligand
sequence F
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

18) chain A
residue 588
type
ligand
sequence T
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

19) chain A
residue 589
type
ligand
sequence A
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

20) chain A
residue 590
type
ligand
sequence V
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

21) chain A
residue 624
type
ligand
sequence T
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

22) chain A
residue 625
type
ligand
sequence L
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

23) chain A
residue 626
type
ligand
sequence P
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

24) chain A
residue 637
type
ligand
sequence V
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

25) chain A
residue 751
type
ligand
sequence W
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

26) chain A
residue 756
type
ligand
sequence W
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

27) chain A
residue 760
type
ligand
sequence S
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

28) chain A
residue 761
type
ligand
sequence Y
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

29) chain A
residue 800
type
ligand
sequence G
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

30) chain A
residue 801
type
ligand
sequence E
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

31) chain A
residue 809
type
ligand
sequence A
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

32) chain A
residue 810
type
ligand
sequence T
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

33) chain A
residue 811
type
ligand
sequence V
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

34) chain A
residue 814
type
ligand
sequence A
description BINDING SITE FOR RESIDUE D70 A 900
source : AC1

35) chain A
residue 309
type BINDING
ligand
sequence A
description FAD.
source Swiss-Prot : SWS_FT_FI1

36) chain A
residue 328
type BINDING
ligand
sequence D
description FAD.
source Swiss-Prot : SWS_FT_FI1

37) chain A
residue 330
type BINDING
ligand
sequence G
description FAD.
source Swiss-Prot : SWS_FT_FI1

38) chain A
residue 336
type BINDING
ligand
sequence G
description FAD.
source Swiss-Prot : SWS_FT_FI1

39) chain A
residue 821
type BINDING
ligand
sequence E
description FAD.
source Swiss-Prot : SWS_FT_FI1

40) chain A
residue 352-353
type NP_BIND
ligand
sequence EL
description FAD.
source Swiss-Prot : SWS_FT_FI2

41) chain A
residue 830-831
type NP_BIND
ligand
sequence LG
description FAD.
source Swiss-Prot : SWS_FT_FI2

42) chain A
residue 301-329
type NP_BIND
ligand
sequence GMDVTLLEARDRVGGRVATFRKGNYVADL
description FAD (Potential).
source Swiss-Prot : SWS_FT_FI3

43) chain A
residue 284-290
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence IGSGVSG
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

44) chain A
residue 307-310
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence LEAR
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

45) chain A
residue 314-317
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence GGRV
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

46) chain A
residue 329-335
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence LGAMVVT
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

47) chain A
residue 538-539
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence FA
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

48) chain A
residue 564
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence H
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

49) chain A
residue 571
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence Y
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

50) chain A
residue 588-590
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence TAV
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

51) chain A
residue 624-626
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence TLP
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

52) chain A
residue 629
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence V
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

53) chain A
residue 637
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence V
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

54) chain A
residue 659
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence L
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

55) chain A
residue 661
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence K
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

56) chain A
residue 751
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence W
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

57) chain A
residue 756
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence W
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

58) chain A
residue 759-761
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence GSY
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

59) chain A
residue 800-801
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence GE
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

60) chain A
residue 808-812
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence PATVH
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900

61) chain A
residue 814
type binding
ligand D70: [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE
sequence A
description [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-2,3,4-TRIHYDROXY-5-[(4AS,10AS)-4A-[(1S,3E)-3-IMINO-1-PHENYLPENTYL]-7,8-DIMETHYL-2,4-DIOXO-1,3,4,4A,5,10A-HEXAHYDROBENZO[G]PTERIDIN-10(2H)-YL]PENTYL DIHYDROGEN DIPHOSPHATE binding site
source pdb_hetatom : D70_4uv9_A_900


Display surface

Download
Links