eF-site ID 4uuu-A PDB Code 4uuu Chain A click to enlarge Title 1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM Classification LYASE Compound CYSTATHIONINE BETA-SYNTHASE Source Homo sapiens (Human) (CBS_HUMAN) Sequence A:  NLYFQSMKPWWWHLRVQELGLSAPLTVLPTITCGHTIEIL REKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQ VGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQQRQ MVFGVVTAIDLLNFVAA Description (1)  CYSTATHIONINE BETA-SYNTHASE (E.C.4.2.1.22) Functional site 1) chain A residue 442 type sequence G description BINDING SITE FOR RESIDUE SAM B 1548 source : AC1 2) chain A residue 444 type sequence D description BINDING SITE FOR RESIDUE SAM B 1548 source : AC1 3) chain A residue 422 type sequence P description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 4) chain A residue 423 type sequence L description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 5) chain A residue 442 type sequence G description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 6) chain A residue 443 type sequence F description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 7) chain A residue 444 type sequence D description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 8) chain A residue 445 type sequence Q description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 9) chain A residue 533 type sequence V description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 10) chain A residue 535 type sequence T description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 11) chain A residue 537 type sequence I description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 12) chain A residue 538 type sequence D description BINDING SITE FOR RESIDUE SAM A 1546 source : AC2 13) chain A residue -3 type sequence Q description BINDING SITE FOR RESIDUE EDO B 1549 source : AC3 14) chain A residue 421 type sequence A description BINDING SITE FOR RESIDUE EDO B 1549 source : AC3 15) chain A residue 530 type sequence V description BINDING SITE FOR RESIDUE EDO B 1549 source : AC3 16) chain A residue 531 type sequence F description BINDING SITE FOR RESIDUE EDO B 1549 source : AC3 17) chain A residue 419 type sequence L description BINDING SITE FOR RESIDUE EDO A 1547 source : AC4 18) chain A residue 420 type sequence S description BINDING SITE FOR RESIDUE EDO A 1547 source : AC4 19) chain A residue 538 type sequence D description BINDING SITE FOR RESIDUE EDO A 1547 source : AC4 20) chain A residue 513 type sequence H description BINDING SITE FOR RESIDUE EDO B 1551 source : AC6 21) chain A residue 530 type sequence V description BINDING SITE FOR RESIDUE EDO B 1551 source : AC6 22) chain A residue 493 type sequence T description BINDING SITE FOR RESIDUE EDO A 1548 source : AC7 23) chain A residue 513 type sequence H description BINDING SITE FOR RESIDUE EDO A 1548 source : AC7 24) chain A residue 514 type sequence E description BINDING SITE FOR RESIDUE EDO A 1548 source : AC7 25) chain A residue 410 type sequence W description BINDING SITE FOR RESIDUE EDO A 1549 source : AC8 26) chain A residue 411 type sequence H description BINDING SITE FOR RESIDUE EDO A 1549 source : AC8 27) chain A residue 515 type sequence Q description BINDING SITE FOR RESIDUE EDO A 1550 source : AC9 28) chain A residue 436 type sequence E description BINDING SITE FOR RESIDUE EDO B 1552 source : BC1 29) chain A residue 440 type sequence E description BINDING SITE FOR RESIDUE EDO B 1552 source : BC1 30) chain A residue 542 type sequence F description BINDING SITE FOR RESIDUE EDO A 1551 source : BC2 31) chain A residue 545 type sequence A description BINDING SITE FOR RESIDUE EDO A 1551 source : BC2 32) chain A residue 439 type sequence R description BINDING SITE FOR RESIDUE EDO A 1552 source : BC3 33) chain A residue 440 type sequence E description BINDING SITE FOR RESIDUE EDO A 1552 source : BC3 34) chain A residue 441 type sequence K description BINDING SITE FOR RESIDUE EDO A 1552 source : BC3 35) chain A residue 442 type sequence G description BINDING SITE FOR RESIDUE EDO A 1552 source : BC3 36) chain A residue 408 type sequence W description BINDING SITE FOR RESIDUE EDO A 1553 source : BC4 37) chain A residue 543 type sequence V description BINDING SITE FOR RESIDUE EDO A 1553 source : BC4

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