eF-site ID 4unc-ABCDEFGHIJKLMNO PDB Code 4unc Chain A, B, C, D, E, F, G, H, I, J, K, L, M, N, O click to enlarge Title THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8 DAYS INCUBATION IN 5MM MN (STATE 6) Classification HYDROLASE/DNA Compound HOMING ENDONUCLEASE I-DMOI Source Desulfurococcus mobilis (4UNC) Sequence A:  VSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSEN LIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKK LYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLKRLR IWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNIS LRDRIKFVHTILSSHLNPLPP B:  GCCTTGCCGGGTAA C:  CGCGCCGGAACTTAC D:  NENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQK SENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVS SKKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLK RLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVL NISLRDRIKFVHTILSSHLNPLPPEAAALEHH E:  GCCTTGCCGGGTAA F:  CGCGCCGGAACTTAC G:  ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS KKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLKR LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN ISLRDRIKFVHTILSS H:  GCCTTGCCGGGTAA I:  CGCGCCGGAACTTAC J:  GTTCCGGCGCG K:  CCGGCAAGGC L:  GTTCCGGCGCG M:  CCGGCAAGGC N:  GTTCCGGCGCG O:  CCGGCAAGGC Description Functional site 1) chain D residue 21 type sequence D description BINDING SITE FOR RESIDUE MN D 1197 source : AC1 2) chain D residue 116 type sequence A description BINDING SITE FOR RESIDUE MN D 1197 source : AC1 3) chain D residue 120 type sequence K description BINDING SITE FOR RESIDUE MN D 1197 source : AC1 4) chain E residue 14 type sequence A description BINDING SITE FOR RESIDUE MN D 1197 source : AC1 5) chain M residue 16 type sequence C description BINDING SITE FOR RESIDUE MN D 1197 source : AC1 6) chain D residue 20 type sequence G description BINDING SITE FOR RESIDUE MN D 1198 source : AC2 7) chain D residue 117 type sequence E description BINDING SITE FOR RESIDUE MN D 1198 source : AC2 8) chain F residue 15 type sequence C description BINDING SITE FOR RESIDUE MN D 1198 source : AC2 9) chain L residue 15 type sequence G description BINDING SITE FOR RESIDUE MN D 1198 source : AC2 10) chain G residue 21 type sequence D description BINDING SITE FOR RESIDUE MN G 1181 source : AC3 11) chain G residue 116 type sequence A description BINDING SITE FOR RESIDUE MN G 1181 source : AC3 12) chain H residue 14 type sequence A description BINDING SITE FOR RESIDUE MN G 1181 source : AC3 13) chain O residue 16 type sequence C description BINDING SITE FOR RESIDUE MN G 1181 source : AC3 14) chain G residue 20 type sequence G description BINDING SITE FOR RESIDUE MN G 1182 source : AC4 15) chain G residue 117 type sequence E description BINDING SITE FOR RESIDUE MN G 1182 source : AC4 16) chain I residue 15 type sequence C description BINDING SITE FOR RESIDUE MN G 1182 source : AC4 17) chain N residue 15 type sequence G description BINDING SITE FOR RESIDUE MN G 1182 source : AC4 18) chain A residue 21 type sequence D description BINDING SITE FOR RESIDUE MN A 1188 source : AC5 19) chain A residue 116 type sequence A description BINDING SITE FOR RESIDUE MN A 1188 source : AC5 20) chain B residue 14 type sequence A description BINDING SITE FOR RESIDUE MN A 1188 source : AC5 21) chain K residue 16 type sequence C description BINDING SITE FOR RESIDUE MN A 1188 source : AC5 22) chain A residue 20 type sequence G description BINDING SITE FOR RESIDUE MN A 1189 source : AC6 23) chain A residue 117 type sequence E description BINDING SITE FOR RESIDUE MN A 1189 source : AC6 24) chain C residue 15 type sequence C description BINDING SITE FOR RESIDUE MN A 1189 source : AC6 25) chain J residue 15 type sequence G description BINDING SITE FOR RESIDUE MN A 1189 source : AC6 26) chain G residue 21 type sequence D description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 27) chain G residue 117 type sequence E description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 28) chain H residue 14 type sequence A description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 29) chain I residue 15 type sequence C description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 30) chain N residue 15 type sequence G description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 31) chain O residue 16 type sequence C description BINDING SITE FOR RESIDUE MN G 1183 source : AC7 32) chain D residue 21 type sequence D description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 33) chain D residue 117 type sequence E description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 34) chain E residue 14 type sequence A description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 35) chain F residue 15 type sequence C description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 36) chain L residue 15 type sequence G description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 37) chain M residue 16 type sequence C description BINDING SITE FOR RESIDUE MN D 1199 source : AC8 38) chain A residue 20 type sequence G description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 39) chain A residue 21 type sequence D description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 40) chain A residue 117 type sequence E description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 41) chain B residue 14 type sequence A description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 42) chain C residue 15 type sequence C description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 43) chain J residue 15 type sequence G description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 44) chain K residue 16 type sequence C description BINDING SITE FOR RESIDUE MN A 1190 source : AC9 45) chain A residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 46) chain A residue 117 type ACT_SITE sequence E description source Swiss-Prot : SWS_FT_FI1 47) chain D residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 48) chain D residue 117 type ACT_SITE sequence E description source Swiss-Prot : SWS_FT_FI1 49) chain G residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 50) chain G residue 117 type ACT_SITE sequence E description source Swiss-Prot : SWS_FT_FI1

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