eF-site ID 4un8-ADG
PDB Code 4un8
Chain A, D, G

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Title THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)
Classification HYDROLASE/DNA
Compound HOMING ENDONUCLEASE I-DMOI
Source Desulfurococcus mobilis (4UN8)
Sequence A:  NENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQK
SENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVS
SKKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLK
RLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVL
NISLRDRIKFVHTILSSHLNPLPP
D:  ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS
ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS
KKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLKR
LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN
ISLRDRIKFVHTILSSHLNPLPPEAAALEHH
G:  EEVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS
ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS
KKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLKR
LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN
ISLRDRIKFVHTILSSH
Description (1)  HOMING ENDONUCLEASE I-DMOI (E.C.3.1.-.-)


Functional site

1) chain A
residue 21
type
ligand
sequence D
description BINDING SITE FOR RESIDUE MN A 1188
source : AC1

2) chain A
residue 116
type
ligand
sequence A
description BINDING SITE FOR RESIDUE MN A 1188
source : AC1

3) chain A
residue 120
type
ligand
sequence K
description BINDING SITE FOR RESIDUE MN A 1188
source : AC1

4) chain A
residue 20
type
ligand
sequence G
description BINDING SITE FOR RESIDUE MN A 1189
source : AC2

5) chain A
residue 117
type
ligand
sequence E
description BINDING SITE FOR RESIDUE MN A 1189
source : AC2

6) chain D
residue 21
type
ligand
sequence D
description BINDING SITE FOR RESIDUE MN D 1197
source : AC3

7) chain D
residue 116
type
ligand
sequence A
description BINDING SITE FOR RESIDUE MN D 1197
source : AC3

8) chain D
residue 20
type
ligand
sequence G
description BINDING SITE FOR RESIDUE MN D 1198
source : AC4

9) chain D
residue 117
type
ligand
sequence E
description BINDING SITE FOR RESIDUE MN D 1198
source : AC4

10) chain G
residue 20
type
ligand
sequence G
description BINDING SITE FOR RESIDUE MN G 1182
source : AC5

11) chain G
residue 117
type
ligand
sequence E
description BINDING SITE FOR RESIDUE MN G 1182
source : AC5

12) chain G
residue 21
type
ligand
sequence D
description BINDING SITE FOR RESIDUE MN G 1183
source : AC6

13) chain G
residue 116
type
ligand
sequence A
description BINDING SITE FOR RESIDUE MN G 1183
source : AC6

14) chain A
residue 21
type ACT_SITE
ligand
sequence D
description
source Swiss-Prot : SWS_FT_FI1

15) chain A
residue 117
type ACT_SITE
ligand
sequence E
description
source Swiss-Prot : SWS_FT_FI1

16) chain D
residue 21
type ACT_SITE
ligand
sequence D
description
source Swiss-Prot : SWS_FT_FI2

17) chain D
residue 117
type ACT_SITE
ligand
sequence E
description
source Swiss-Prot : SWS_FT_FI2

18) chain G
residue 21
type ACT_SITE
ligand
sequence D
description
source Swiss-Prot : SWS_FT_FI3

19) chain G
residue 117
type ACT_SITE
ligand
sequence E
description
source Swiss-Prot : SWS_FT_FI3


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