eF-site ID 4uin-HL PDB Code 4uin Chain H, L click to enlarge Title crystal structure of quinine-dependent Fab 314.3 with quinine Classification IMMUNE SYSTEM Compound FAB 314.3 Source ORGANISM_COMMON: HOUSE MOUSE; ORGANISM_SCIENTIFIC: MUS MUSCULUS; Sequence H:  EVQLQQSGTVLARPGASVKMSCEASGYTFTSYWMHWLKKR PGQGLEWIGTIYPGNSDSSYNQRFKGKAKLTAVTSTSTAY MELSSLTNEDSAVYYCTRERGLYYGGRSFDYWGQGTTLTV SSAKTTPPSVYPLAPGSNSMVTLGCLVKGYFPEPVTVTWN SGSLSSGVHTFPAVLESDLYTLSSSVTVPSSPRPSETVTC NVAHPASSTKVDKKIVPRDCG L:  DIQMTQTTSSLSASLGDRVTISCRASQDISNYLTWYQQKP DGTVKLLIYYTSKLHSGVPSRFSGSGSGTDYSLTISNLEQ EDVANYFCQQGNSLPPTFGGGTKLEIKRADAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC Description Functional site 1) chain H residue 50 type sequence T description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 2) chain H residue 99 type sequence E description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 3) chain H residue 104 type sequence Y description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 4) chain H residue 106 type sequence G description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 5) chain H residue 107 type sequence R description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 6) chain H residue 109 type sequence F description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 7) chain L residue 91 type sequence G description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 8) chain L residue 94 type sequence L description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 9) chain L residue 96 type sequence P description BINDING SITE FOR RESIDUE QI9 H 1226 source : AC1 10) chain L residue 192-198 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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