eF-site ID 4ucz-AB PDB Code 4ucz Chain A, B click to enlarge Title X-ray structure and activities of an essential Mononegavirales L- protein domain Classification TRANSFERASE Compound RNA-DIRECTED RNA POLYMERASE L Source (Q91L20_9MONO) Sequence A:  IDPTEQLAYFPKITFERLKNYDTSSNYAKGKLTRNYMILL PWQHVNRYNFVFSSTGCKVSLKTCIGKLMKDLNPKVLYFI GEGAGNWMARTACEYPDIKFVYRSLKDDLDHHYPLEYQRV IGELSRIIDSGEGLSMETTDATQKTHWDLIHRVSKDALLI TLCDAEFKDRDDFFKMVILWRKHVLSCRICTTYGTDLYLF AKYHAKDCNVKLPFFVRSVATFIMQGSKLSGSECYILLTL GHHNNLPCHGEIQNSKMKIAVCNDFYAAKKLDNKSIEANC KSLLSGLRIPINKKELNRQRRLLTLQSNSKVIESKWLTNK ANTIIDWLEHILNSPKGELNYDFFEALENTYPNMIKLIDN LGNAEIKKLIKVTGYMLVSKK B:  QVIDPTEQLAYFPKITFERLKNYDTSSNYAKGKLTRNYMI LLPWQHVNRYNFVFSSTGCKVSLKTCIGKLMKDLNPKVLY FIGEGAGNWMARTACEYPDIKFVYRSLKDDLDHHYPLEYQ RVIGELSRIIDSGEGLSMETTDATQKTHWDLIHRVSKDAL LITLCDAEFKDRDDFFKMVILWRKHVLSCRICTTYGTDLY LFAKYHAKDCNVKLPFFVRSVATFIMQGSKLSGSECYILL TLGHHNNLPCHGEIQNSKMKIAVCNDFYAAKKLDNKSIEA NCKSLLSGLRIPINKKELNRQRRLLTLSKWLTNKANTIID WLEHILNSPKGELNYDFFEALENTYPNMIKLIDNLGNAEI KKLIKVTGYMLVSKK Description (1)  RNA-DIRECTED RNA POLYMERASE L Functional site 1) chain A residue 1766 type sequence H description BINDING SITE FOR RESIDUE ZN A 2408 source : AC1 2) chain A residue 1798 type sequence H description BINDING SITE FOR RESIDUE ZN A 2408 source : AC1 3) chain A residue 1802 type sequence C description BINDING SITE FOR RESIDUE ZN A 2408 source : AC1 4) chain A residue 1805 type sequence C description BINDING SITE FOR RESIDUE ZN A 2408 source : AC1 5) chain B residue 1766 type sequence H description BINDING SITE FOR RESIDUE ZN B 2408 source : AC2 6) chain B residue 1798 type sequence H description BINDING SITE FOR RESIDUE ZN B 2408 source : AC2 7) chain B residue 1802 type sequence C description BINDING SITE FOR RESIDUE ZN B 2408 source : AC2 8) chain B residue 1805 type sequence C description BINDING SITE FOR RESIDUE ZN B 2408 source : AC2 9) chain A residue 1658 type sequence Q description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 10) chain A residue 1659 type sequence H description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 11) chain A residue 1662 type sequence R description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 12) chain A residue 1667 type sequence F description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 13) chain A residue 1668 type sequence S description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 14) chain A residue 1669 type sequence S description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 15) chain A residue 1673 type sequence K description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 16) chain A residue 1841 type sequence G description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 17) chain A residue 1842 type sequence S description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 18) chain A residue 1843 type sequence K description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 19) chain A residue 1988 type sequence A description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 20) chain A residue 1991 type sequence K description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 21) chain A residue 1992 type sequence K description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 22) chain A residue 1995 type sequence K description BINDING SITE FOR RESIDUE GTP A 2409 source : AC3 23) chain B residue 1658 type sequence Q description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 24) chain B residue 1659 type sequence H description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 25) chain B residue 1662 type sequence R description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 26) chain B residue 1666 type sequence V description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 27) chain B residue 1667 type sequence F description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 28) chain B residue 1668 type sequence S description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 29) chain B residue 1669 type sequence S description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 30) chain B residue 1673 type sequence K description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 31) chain B residue 1841 type sequence G description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 32) chain B residue 1991 type sequence K description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4 33) chain B residue 1995 type sequence K description BINDING SITE FOR RESIDUE GMP B 2409 source : AC4

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