eF-site/Summary 4u8l-B

eF-site ID	4u8l-B
PDB Code	4u8l
Chain	B

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Title	Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant N207A
Classification	ISOMERASE
Compound	UDP-galactopyranose mutase
Source	(Q4W1X2_ASPFM)

Sequence	B:	HPDISVDVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNET PGGLASTDVTPEGFLYDVGGHVIFSHYKYFDDCLDEALPK EDDWYTHQRISYVRCQGQWVPYPFQNNISMLPKEEQVKCI DGMIDAALEARVANTKPKTFDEWIVRMMGTGIADLFMRPY NFKVWAVPTTKMQCAWLGERVAAPNLKAVTTNVILGKTAG NWGPAATFRFPARGGTGGIWIAVANTLPKEKTRFGEKGKV TKVNANNKTVTLQDGTTIGYKKLVSTMAVDFLAEAMNDQE LVGLTKQLFYSSTHVIGVGVRGSRPERIGDKCWLYFPEDN CPFYRATIFSNYSPYNQPEASAALPTMQLADGSRPQSTEA KEGPYWSIMLEVSESSMKPVNQETILADCIQGLVNTEMLK PTDEIVSTYHRRFDHGYPTPTLEREGTLTQILPKLQDKDI WSRGRFGSWRYEVGNQDHSFMLGVEAVDNIVNGAVELTLN YPDFVNGRQNTERRLVDGAQVFAKS

Description

Functional site


1)	chain	B
	residue	14
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

2)	chain	B
	residue	16
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

3)	chain	B
	residue	17
	type
	sequence	P
	description	binding site for residue FDA B 601
	source	: AD2

4)	chain	B
	residue	18
	type
	sequence	T
	description	binding site for residue FDA B 601
	source	: AD2

5)	chain	B
	residue	38
	type
	sequence	D
	description	binding site for residue FDA B 601
	source	: AD2

6)	chain	B
	residue	39
	type
	sequence	S
	description	binding site for residue FDA B 601
	source	: AD2

7)	chain	B
	residue	45
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

8)	chain	B
	residue	46
	type
	sequence	L
	description	binding site for residue FDA B 601
	source	: AD2

9)	chain	B
	residue	47
	type
	sequence	A
	description	binding site for residue FDA B 601
	source	: AD2

10)	chain	B
	residue	60
	type
	sequence	V
	description	binding site for residue FDA B 601
	source	: AD2

11)	chain	B
	residue	62
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

12)	chain	B
	residue	63
	type
	sequence	H
	description	binding site for residue FDA B 601
	source	: AD2

13)	chain	B
	residue	64
	type
	sequence	V
	description	binding site for residue FDA B 601
	source	: AD2

14)	chain	B
	residue	240
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

15)	chain	B
	residue	242
	type
	sequence	V
	description	binding site for residue FDA B 601
	source	: AD2

16)	chain	B
	residue	373
	type
	sequence	E
	description	binding site for residue FDA B 601
	source	: AD2

17)	chain	B
	residue	446
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

18)	chain	B
	residue	447
	type
	sequence	R
	description	binding site for residue FDA B 601
	source	: AD2

19)	chain	B
	residue	456
	type
	sequence	G
	description	binding site for residue FDA B 601
	source	: AD2

20)	chain	B
	residue	457
	type
	sequence	N
	description	binding site for residue FDA B 601
	source	: AD2

21)	chain	B
	residue	458
	type
	sequence	Q
	description	binding site for residue FDA B 601
	source	: AD2

22)	chain	B
	residue	461
	type
	sequence	S
	description	binding site for residue FDA B 601
	source	: AD2

23)	chain	B
	residue	307
	type
	sequence	P
	description	binding site for residue SO4 B 602
	source	: AD3

24)	chain	B
	residue	308
	type
	sequence	E
	description	binding site for residue SO4 B 602
	source	: AD3

25)	chain	B
	residue	309
	type
	sequence	R
	description	binding site for residue SO4 B 602
	source	: AD3

26)	chain	B
	residue	402
	type
	sequence	K
	description	binding site for residue SO4 B 602
	source	: AD3

27)	chain	B
	residue	114
	type
	sequence	P
	description	binding site for residue SO4 B 603
	source	: AD4

28)	chain	B
	residue	115
	type
	sequence	K
	description	binding site for residue SO4 B 603
	source	: AD4

29)	chain	B
	residue	383
	type
	sequence	N
	description	binding site for residue SO4 B 603
	source	: AD4

30)	chain	B
	residue	386
	type
	sequence	T
	description	binding site for residue SO4 B 603
	source	: AD4

31)	chain	B
	residue	40
	type
	sequence	N
	description	binding site for residue SO4 B 604
	source	: AD5

32)	chain	B
	residue	50
	type
	sequence	D
	description	binding site for residue SO4 B 604
	source	: AD5

33)	chain	B
	residue	413
	type
	sequence	R
	description	binding site for residue SO4 B 604
	source	: AD5

34)	chain	B
	residue	87
	type
	sequence	Y
	description	binding site for residue SO4 B 605
	source	: AD6

35)	chain	B
	residue	88
	type
	sequence	T
	description	binding site for residue SO4 B 605
	source	: AD6

36)	chain	B
	residue	496
	type
	sequence	R
	description	binding site for residue SO4 B 606
	source	: AD7

37)	chain	B
	residue	147
	type
	sequence	V
	description	binding site for residue SO4 B 607
	source	: AD8

38)	chain	B
	residue	152
	type
	sequence	T
	description	binding site for residue SO4 B 607
	source	: AD8

39)	chain	B
	residue	160
	type
	sequence	R
	description	binding site for residue SO4 B 607
	source	: AD8

40)	chain	B
	residue	91
	type
	sequence	R
	description	binding site for residue SO4 B 608
	source	: AD9

41)	chain	B
	residue	104
	type
	sequence	Y
	description	binding site for residue SO4 B 608
	source	: AD9

42)	chain	B
	residue	203
	type
	sequence	N
	description	binding site for residue SO4 B 608
	source	: AD9

43)	chain	B
	residue	322
	type
	sequence	N
	description	binding site for residue EDO B 609
	source	: AE1

44)	chain	B
	residue	323
	type
	sequence	C
	description	binding site for residue EDO B 609
	source	: AE1

45)	chain	B
	residue	324
	type
	sequence	P
	description	binding site for residue EDO B 609
	source	: AE1

46)	chain	B
	residue	390
	type
	sequence	D
	description	binding site for residue EDO B 609
	source	: AE1

47)	chain	B
	residue	443
	type
	sequence	W
	description	binding site for residue EDO B 610
	source	: AE2

48)	chain	B
	residue	471
	type
	sequence	N
	description	binding site for residue EDO B 610
	source	: AE2

49)	chain	B
	residue	62
	type
	sequence	G
	description	binding site for residue EDO B 611
	source	: AE3

50)	chain	B
	residue	315
	type
	sequence	W
	description	binding site for residue EDO B 611
	source	: AE3

51)	chain	B
	residue	327
	type
	sequence	R
	description	binding site for residue EDO B 611
	source	: AE3

52)	chain	B
	residue	98
	type
	sequence	Q
	description	binding site for residue EDO B 612
	source	: AE4

53)	chain	B
	residue	116
	type
	sequence	E
	description	binding site for residue EDO B 612
	source	: AE4

54)	chain	B
	residue	117
	type
	sequence	E
	description	binding site for residue EDO B 612
	source	: AE4

55)	chain	B
	residue	321
	type
	sequence	D
	description	binding site for residue EDO B 612
	source	: AE4

56)	chain	B
	residue	323
	type
	sequence	C
	description	binding site for residue EDO B 612
	source	: AE4

57)	chain	B
	residue	324
	type
	sequence	P
	description	binding site for residue EDO B 612
	source	: AE4

58)	chain	B
	residue	114
	type
	sequence	P
	description	binding site for residue EDO B 613
	source	: AE5

59)	chain	B
	residue	116
	type
	sequence	E
	description	binding site for residue EDO B 613
	source	: AE5

60)	chain	B
	residue	324
	type
	sequence	P
	description	binding site for residue EDO B 613
	source	: AE5

61)	chain	B
	residue	390
	type
	sequence	D
	description	binding site for residue EDO B 613
	source	: AE5

62)	chain	B
	residue	117
	type
	sequence	E
	description	binding site for residue EDO B 614
	source	: AE6

63)	chain	B
	residue	120
	type
	sequence	K
	description	binding site for residue EDO B 614
	source	: AE6

64)	chain	B
	residue	427
	type
	sequence	E
	description	binding site for residue EDO B 615
	source	: AE7

65)	chain	B
	residue	452
	type
	sequence	R
	description	binding site for residue EDO B 615
	source	: AE7

66)	chain	B
	residue	482
	type
	sequence	N
	description	binding site for residue EDO B 615
	source	: AE7

67)	chain	B
	residue	484
	type
	sequence	P
	description	binding site for residue EDO B 615
	source	: AE7

68)	chain	B
	residue	149
	type
	sequence	M
	description	binding site for residue EDO B 616
	source	: AE8

69)	chain	B
	residue	187
	type
	sequence	N
	description	binding site for residue EDO B 616
	source	: AE8

70)	chain	B
	residue	494
	type
	sequence	E
	description	binding site for residue EDO D 609
	source	: AH1

71)	chain	B
	residue	38
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

72)	chain	B
	residue	46
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

73)	chain	B
	residue	63
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

74)	chain	B
	residue	242
	type	BINDING
	sequence	V
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

75)	chain	B
	residue	456
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

76)	chain	B
	residue	458
	type	BINDING
	sequence	Q
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

77)	chain	B
	residue	461
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

78)	chain	B
	residue	18
	type	BINDING
	sequence	T
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKA, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKK, ECO:0007744\|PDB:3UKL, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UTE
	source	Swiss-Prot : SWS_FT_FI1

79)	chain	B
	residue	61
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKP
	source	Swiss-Prot : SWS_FT_FI2

80)	chain	B
	residue	62
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ
	source	Swiss-Prot : SWS_FT_FI3

81)	chain	B
	residue	93
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

82)	chain	B
	residue	203
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

83)	chain	B
	residue	315
	type	BINDING
	sequence	W
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

84)	chain	B
	residue	447
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

85)	chain	B
	residue	460
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

86)	chain	B
	residue	68
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

87)	chain	B
	residue	91
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:23036087, ECO:0007744\|PDB:5VWT
	source	Swiss-Prot : SWS_FT_FI4

88)	chain	B
	residue	107
	type	BINDING
	sequence	Q
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

89)	chain	B
	residue	163
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

90)	chain	B
	residue	167
	type	BINDING
	sequence	W
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

91)	chain	B
	residue	182
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

92)	chain	B
	residue	207
	type	BINDING
	sequence	A
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

93)	chain	B
	residue	419
	type	BINDING
	sequence	Y
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

94)	chain	B
	residue	453
	type	BINDING
	sequence	Y
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

95)	chain	B
	residue	104
	type	BINDING
	sequence	Y
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI5

96)	chain	B
	residue	159
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP
	source	Swiss-Prot : SWS_FT_FI6

97)	chain	B
	residue	162
	type	BINDING
	sequence	Y
	description	BINDING => ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKP
	source	Swiss-Prot : SWS_FT_FI6

98)	chain	B
	residue	317
	type	BINDING
	sequence	Y
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UKQ, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI7

99)	chain	B
	residue	327
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:22294687, ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKF, ECO:0007744\|PDB:3UKH, ECO:0007744\|PDB:3UTH
	source	Swiss-Prot : SWS_FT_FI8

100)	chain	B
	residue	457
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:22334662, ECO:0007744\|PDB:3UKH
	source	Swiss-Prot : SWS_FT_FI9