|
eF-site ID
|
4u2u-AB |
PDB Code
|
4u2u |
Chain
|
A, B |
|
click to enlarge
|
|
Title
|
Bak domain swapped dimer induced by BidBH3 with CHAPS |
Classification
|
APOPTOSIS |
Compound
|
Bcl-2 homologous antagonist/killer |
Source
|
(BAK_HUMAN) |
|
Sequence
|
A: |
SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEPSSTMGQVGR
QLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIAT
SLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTR
FVVDFMLHHSIARWIAQRGGWVAALN
|
B: |
MSEEQVAQDTEEVFRSYVFYRHQQEQESTMGQVGRQLAII
GDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFES
GINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDF
MLHHSIARWIAQRGGWVAALN
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
160 |
type |
BINDING |
sequence |
D
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
A |
residue |
164 |
type |
BINDING |
sequence |
H
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
B |
residue |
160 |
type |
BINDING |
sequence |
D
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
4)
|
chain |
B |
residue |
164 |
type |
BINDING |
sequence |
H
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
5)
|
chain |
A |
residue |
118-136 |
type |
prosite |
sequence |
LFESGINWGRVVALLGFGY
|
description |
BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFeSGi.NWGRVVALLgFGY
|
source |
prosite : PS01080
|
|
6)
|
chain |
A |
residue |
170-181 |
type |
prosite |
sequence |
WIAQRGGWVAAL
|
description |
BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIaqrGGWVaAL
|
source |
prosite : PS01258
|
|
7)
|
chain |
A |
residue |
74-88 |
type |
prosite |
sequence |
VGRQLAIIGDDINRR
|
description |
BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAiIGDDINRR
|
source |
prosite : PS01259
|
|
|
|