eF-site/Summary 4u1l-B

eF-site ID	4u1l-B
PDB Code	4u1l
Chain	B

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Title	HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Classification	IMMUNE SYSTEM
Compound	HLA class I histocompatibility antigen, B-81 alpha chain
Source	Homo sapiens (Human) (Q90VG9_9HIV1)

Sequence	B:	MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDL LKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA CRVNHVTLSQPKIVKWDRDM

Description

Functional site


1)	chain	B
	residue	60
	type
	sequence	W
	description	binding site for residue EDO A 307
	source	: AC7

2)	chain	B
	residue	57
	type
	sequence	S
	description	binding site for residue EDO B 101
	source	: AD1

3)	chain	B
	residue	58
	type
	sequence	K
	description	binding site for residue EDO B 101
	source	: AD1

4)	chain	B
	residue	2
	type	MOD_RES
	sequence	Q
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

5)	chain	B
	residue	1
	type	CARBOHYD
	sequence	I
	description	N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI2

6)	chain	B
	residue	19
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

7)	chain	B
	residue	41
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

8)	chain	B
	residue	48
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

9)	chain	B
	residue	58
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

10)	chain	B
	residue	91
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

11)	chain	B
	residue	94
	type	CARBOHYD
	sequence	K
	description	N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI3

12)	chain	B
	residue	78-84
	type	prosite
	sequence	YACRVNH
	description	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVQH
	source	prosite : PS00290