eF-site ID 4tmf-AB PDB Code 4tmf Chain A, B click to enlarge Title Crystal structure of human CD38 in complex with hydrolysed compound JMS713 Classification Hydrolase/Hydrolase Inhibitor Compound ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Source (CD38_HUMAN) Sequence A:  QTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWD AFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILLWSR IKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFDTSK INYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVM LDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVIHGRD LCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPE DSSC B:  EFWRQTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQ SVWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKIL LWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEF DTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDV VHVMLDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVI HRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVK NP Description Functional site 1) chain A residue 164 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 2) chain B residue 164 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 3) chain A residue 219 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 source Swiss-Prot : SWS_FT_FI4 4) chain B residue 219 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 source Swiss-Prot : SWS_FT_FI4 5) chain A residue 119 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 201 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 7) chain B residue 119 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 8) chain B residue 201 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 100 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2 10) chain A residue 209 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 100 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 209 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links