|
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eF-site ID
|
4tmf-A |
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PDB Code
|
4tmf |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of human CD38 in complex with hydrolysed compound JMS713 |
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Classification
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Hydrolase/Hydrolase Inhibitor |
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Compound
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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
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Source
|
(CD38_HUMAN) |
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Sequence
|
A: |
QTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWD
AFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILLWSR
IKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFDTSK
INYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVM
LDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVIHGRD
LCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPE
DSSC
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
119 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
ACT_SITE => ECO:0000305|PubMed:7961800
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
201 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
ACT_SITE => ECO:0000305|PubMed:7961800
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
100 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
209 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
164 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
A |
| residue |
219 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
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