|
|
eF-site ID
|
4rzs-A |
|
PDB Code
|
4rzs |
|
Chain
|
A |
|
click to enlarge
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Title
|
Lac repressor engineered to bind sucralose, unliganded tetramer |
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Classification
|
TRANSCRIPTION |
|
Compound
|
Lac repressor |
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Source
|
(C9QQT3_ECOD1) |
|
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Sequence
|
A: |
PVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAM
AELNYIPNRSLLIGVATSSLALHAPSQIVAAIKSRADQLG
ASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQ
DAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGV
EHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQ
PIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMAL
GAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQ
DFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLA
PNTQTASPRALADSLMQLARQVSRLES
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
A |
| residue |
197 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE GOL A 501
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
246 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE GOL A 501
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
274 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE GOL A 501
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
291 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE GOL A 501
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
6-24 |
| type |
prosite |
| sequence |
LYDVAEYAGVSYQTVSRVV
|
| description |
HTH_LACI_1 LacI-type HTH domain signature. LyDVAeyAgVSyqTVsrVV
|
| source |
prosite : PS00356
|
|
|
6)
|
chain |
A |
| residue |
6-25 |
| type |
DNA_BIND |
| sequence |
LYDVAEYAGVSYQTVSRVVN
|
| description |
H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00111
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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|