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|
eF-site ID
|
4rwy-L |
|
PDB Code
|
4rwy |
|
Chain
|
L |
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click to enlarge
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Title
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Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 |
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Classification
|
VIRAL PROTEIN/IMMUNE SYSTEM |
|
Compound
|
HIV-1 YU2 gp120 |
|
Source
|
(4RWY) |
|
|
Sequence
|
L: |
EIVLTQSPATLSLSPGERATLSCRASQGLNFVVWYQQKRG
QAPRLLIHAPSGRAPGVPDRFSARGSGTEFSLVISSVEPD
DFAIYYCQEYSSTPYNFGPGTRVDRKRTVAAPSVFIFPPS
DEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQE
SVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGL
RSPVTKSFNRGEC
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Description
|
(1) |
HIV-1 YU2 gp120, Antibody 8ANC131 heavy chain, Antibody 8ANC131 light chain
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
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