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eF-site ID
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4rwy-H |
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PDB Code
|
4rwy |
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Chain
|
H |
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click to enlarge
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Title
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Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 |
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Classification
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VIRAL PROTEIN/IMMUNE SYSTEM |
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Compound
|
HIV-1 YU2 gp120 |
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Source
|
(4RWY) |
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Sequence
|
H: |
QGQLVQSGGGLKKPGTSVTISCLASEYTFNEFVIHWIRQA
PGQGPLWLGLIKRSGRLMTAYNFQDRLSLRRDRSTGTVFM
ELRGLRPDDTAVYYCARDGLGEVAPDYRYGIDVWGQGSTV
IVTSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKAEPKSC
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Description
|
(1) |
HIV-1 YU2 gp120, Antibody 8ANC131 heavy chain, Antibody 8ANC131 light chain
|
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Functional site
|
|
|
1)
|
chain |
H |
| residue |
194-200 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
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