eF-site ID 4rwy-A PDB Code 4rwy Chain A click to enlarge Title Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 Classification VIRAL PROTEIN/IMMUNE SYSTEM Compound HIV-1 YU2 gp120 Source (4RWY) Sequence A:  VWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQE VKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLT GGSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGT GPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSEN FTNNAKTIIVQLNESVVINCTRPNNDIRQAHCNLSKTQWE NTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCG GEFFYCNSTQLFTWNGRNITLPCRIKQIINMWQEVGKAMY APPIRGQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDM RDNWRSELYKYKVVKIE Description (1)  HIV-1 YU2 gp120, Antibody 8ANC131 heavy chain, Antibody 8ANC131 light chain Functional site 1) chain A residue 88 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 2) chain A residue 327 type CARBOHYD sequence R description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 348 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 4) chain A residue 362 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 375 type CARBOHYD sequence S description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 381 type CARBOHYD sequence E description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 387 type CARBOHYD sequence S description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 425 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 449 type CARBOHYD sequence I description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 479 type CARBOHYD sequence W description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 487 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 203 type CARBOHYD sequence Q description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 209 type CARBOHYD sequence S description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 212 type CARBOHYD sequence P description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 228 type CARBOHYD sequence C description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 16) chain A residue 232 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 258 type CARBOHYD sequence Q description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 267 type CARBOHYD sequence E description N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04083 source Swiss-Prot : SWS_FT_FI1

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