|
|
eF-site ID
|
4rm8-B |
|
PDB Code
|
4rm8 |
|
Chain
|
B |
|
click to enlarge
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|
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Title
|
Crystal structure of human ezrin in space group P21 |
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Classification
|
PEPTIDE BINDING PROTEIN |
|
Compound
|
Ezrin |
|
Source
|
Homo sapiens (Human) (EZRI_HUMAN) |
|
|
Sequence
|
B: |
KPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREV
WYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRA
KFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETA
VLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHK
LTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYG
INYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPW
SEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQ
LCMGNHELYMRRRKPEKRITEAEKNERVQRQLLTLSSELS
QARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQR
IDEFEAL
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
535 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P26040
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
2)
|
chain |
B |
| residue |
567 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine; by ROCK2 and PKC/PRKCI => ECO:0000305|PubMed:18270268
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
3)
|
chain |
B |
| residue |
60 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
146 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by PDGFR => ECO:0000269|PubMed:1382070, ECO:0000269|PubMed:18046454
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|