eF-site ID 4rjj-G PDB Code 4rjj Chain G click to enlarge Title Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form II Classification LYASE Compound Acetolactate synthase Source Bacillus subtilis PY79 (V5MX36_BACIU) Sequence G:  KNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGP EIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLA TGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNAALFQ PITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQ DVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKL PVVLVGMKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTLS RDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEYD PKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTI NHIEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKSD RAHPLEIVKELRNAVDDHVTVTCDIGSHAIWMSRYFRSYE PLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGG FLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYN RTSAVDFGNIDIVKYAESFGATGLRVESPDQLADVLRQGM NAEGPVIIDVPVDYSDNINLASDKLPKEFGELMK Description Functional site 1) chain G residue 398 type sequence I description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 2) chain G residue 399 type sequence G description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 3) chain G residue 400 type sequence S description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 4) chain G residue 401 type sequence H description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 5) chain G residue 424 type sequence Q description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 6) chain G residue 426 type sequence L description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 7) chain G residue 450 type sequence G description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 8) chain G residue 451 type sequence D description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 9) chain G residue 452 type sequence G description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 10) chain G residue 453 type sequence G description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 11) chain G residue 478 type sequence D description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 12) chain G residue 480 type sequence T description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 13) chain G residue 481 type sequence Y description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 14) chain G residue 482 type sequence D description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 15) chain G residue 483 type sequence M description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 16) chain G residue 484 type sequence V description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 17) chain G residue 547 type sequence Y description BINDING SITE FOR RESIDUE TPP G 601 source : EC3 18) chain G residue 451 type sequence D description BINDING SITE FOR RESIDUE MG G 602 source : EC4 19) chain G residue 478 type sequence D description BINDING SITE FOR RESIDUE MG G 602 source : EC4 20) chain G residue 480 type sequence T description BINDING SITE FOR RESIDUE MG G 602 source : EC4 21) chain G residue 73 type sequence R description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 22) chain G residue 75 type sequence T description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 23) chain G residue 76 type sequence G description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 24) chain G residue 105 type sequence P description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 25) chain G residue 160 type sequence S description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 26) chain G residue 224 type sequence R description BINDING SITE FOR RESIDUE PG4 G 603 source : EC5 27) chain G residue 203 type sequence A description BINDING SITE FOR RESIDUE PG4 G 604 source : EC6 28) chain G residue 207 type sequence K description BINDING SITE FOR RESIDUE PG4 G 604 source : EC6 29) chain G residue 304 type sequence T description BINDING SITE FOR RESIDUE PG4 G 604 source : EC6 30) chain G residue 322 type sequence D description BINDING SITE FOR RESIDUE PG4 G 604 source : EC6 31) chain G residue 393 type sequence T description BINDING SITE FOR RESIDUE PG4 G 605 source : EC7 32) chain G residue 415 type sequence L description BINDING SITE FOR RESIDUE PG4 G 605 source : EC7 33) chain G residue 439 type sequence V description BINDING SITE FOR RESIDUE PG4 G 605 source : EC7 34) chain G residue 440 type sequence K description BINDING SITE FOR RESIDUE PG4 G 605 source : EC7 35) chain G residue 443 type sequence E description BINDING SITE FOR RESIDUE PG4 G 605 source : EC7 36) chain G residue 364 type sequence E description BINDING SITE FOR RESIDUE PG4 G 606 source : EC8 37) chain G residue 382 type sequence K description BINDING SITE FOR RESIDUE PG4 G 606 source : EC8 38) chain G residue 408 type sequence Y description BINDING SITE FOR RESIDUE PG4 G 606 source : EC8 39) chain G residue 410 type sequence R description BINDING SITE FOR RESIDUE PG4 G 606 source : EC8 40) chain G residue 37 type sequence P description BINDING SITE FOR RESIDUE TPP H 601 source : EC9 41) chain G residue 61 type sequence E description BINDING SITE FOR RESIDUE TPP H 601 source : EC9 42) chain G residue 87 type sequence P description BINDING SITE FOR RESIDUE TPP H 601 source : EC9 43) chain G residue 91 type sequence N description BINDING SITE FOR RESIDUE TPP H 601 source : EC9 44) chain G residue 124 type sequence Q description BINDING SITE FOR RESIDUE TPP H 601 source : EC9 45) chain G residue 121 type sequence R description BINDING SITE FOR RESIDUE PG4 H 603 source : FC2 46) chain G residue 125 type sequence S description BINDING SITE FOR RESIDUE PG4 H 603 source : FC2

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