eF-site ID 4rjj-E PDB Code 4rjj Chain E click to enlarge Title Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form II Classification LYASE Compound Acetolactate synthase Source Bacillus subtilis PY79 (V5MX36_BACIU) Sequence E:  VKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKG PEIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNL ATGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNAALF QPITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFP QDVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAK LPVVLVGMKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTL SRDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEY DPKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPST INHIEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKS DRAHPLEIVKELRNAVDDHVTVTCDIGSHAIWMSRYFRSY EPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDG GFLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKY NRTSAVDFGNIDIVKYAESFGATGLRVESPDQLADVLRQG MNAEGPVIIDVPVDYSDNINLASDKLPKEFGELMK Description Functional site 1) chain E residue 203 type sequence A description BINDING SITE FOR RESIDUE PG4 D 603 source : CC3 2) chain E residue 207 type sequence K description BINDING SITE FOR RESIDUE PG4 D 603 source : CC3 3) chain E residue 304 type sequence T description BINDING SITE FOR RESIDUE PG4 D 603 source : CC3 4) chain E residue 322 type sequence D description BINDING SITE FOR RESIDUE PG4 D 603 source : CC3 5) chain E residue 442 type sequence G description BINDING SITE FOR RESIDUE PG4 D 604 source : CC4 6) chain E residue 444 type sequence K description BINDING SITE FOR RESIDUE PG4 D 604 source : CC4 7) chain E residue 470 type sequence P description BINDING SITE FOR RESIDUE PG4 D 604 source : CC4 8) chain E residue 534 type sequence N description BINDING SITE FOR RESIDUE PG4 D 604 source : CC4 9) chain E residue 27 type sequence E description BINDING SITE FOR RESIDUE PG4 D 605 source : CC5 10) chain E residue 398 type sequence I description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 11) chain E residue 399 type sequence G description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 12) chain E residue 400 type sequence S description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 13) chain E residue 401 type sequence H description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 14) chain E residue 424 type sequence Q description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 15) chain E residue 426 type sequence L description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 16) chain E residue 450 type sequence G description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 17) chain E residue 451 type sequence D description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 18) chain E residue 452 type sequence G description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 19) chain E residue 453 type sequence G description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 20) chain E residue 478 type sequence D description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 21) chain E residue 480 type sequence T description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 22) chain E residue 481 type sequence Y description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 23) chain E residue 482 type sequence D description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 24) chain E residue 483 type sequence M description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 25) chain E residue 484 type sequence V description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 26) chain E residue 547 type sequence Y description BINDING SITE FOR RESIDUE TPP E 601 source : CC9 27) chain E residue 451 type sequence D description BINDING SITE FOR RESIDUE MG E 602 source : DC1 28) chain E residue 478 type sequence D description BINDING SITE FOR RESIDUE MG E 602 source : DC1 29) chain E residue 480 type sequence T description BINDING SITE FOR RESIDUE MG E 602 source : DC1 30) chain E residue 386 type sequence N description BINDING SITE FOR RESIDUE PG4 E 603 source : DC2 31) chain E residue 387 type sequence A description BINDING SITE FOR RESIDUE PG4 E 603 source : DC2 32) chain E residue 388 type sequence V description BINDING SITE FOR RESIDUE PG4 E 603 source : DC2 33) chain E residue 389 type sequence D description BINDING SITE FOR RESIDUE PG4 E 603 source : DC2 34) chain E residue 390 type sequence D description BINDING SITE FOR RESIDUE PG4 E 603 source : DC2 35) chain E residue 424 type sequence Q description BINDING SITE FOR RESIDUE PG4 E 604 source : DC3 36) chain E residue 483 type sequence M description BINDING SITE FOR RESIDUE PG4 E 604 source : DC3 37) chain E residue 487 type sequence Q description BINDING SITE FOR RESIDUE PG4 E 604 source : DC3 38) chain E residue 74 type sequence L description BINDING SITE FOR RESIDUE PG4 E 605 source : DC4 39) chain E residue 225 type sequence P description BINDING SITE FOR RESIDUE PG4 E 605 source : DC4 40) chain E residue 439 type sequence V description BINDING SITE FOR RESIDUE PG4 E 605 source : DC4 41) chain E residue 440 type sequence K description BINDING SITE FOR RESIDUE PG4 E 605 source : DC4 42) chain E residue 443 type sequence E description BINDING SITE FOR RESIDUE PG4 E 605 source : DC4 43) chain E residue 100 type sequence N description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 44) chain E residue 101 type sequence T description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 45) chain E residue 163 type sequence Q description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 46) chain E residue 288 type sequence D description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 47) chain E residue 290 type sequence I description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 48) chain E residue 311 type sequence I description BINDING SITE FOR RESIDUE PG4 E 606 source : DC5 49) chain E residue 364 type sequence E description BINDING SITE FOR RESIDUE PG4 E 607 source : DC6 50) chain E residue 382 type sequence K description BINDING SITE FOR RESIDUE PG4 E 607 source : DC6 51) chain E residue 408 type sequence Y description BINDING SITE FOR RESIDUE PG4 E 607 source : DC6 52) chain E residue 410 type sequence R description BINDING SITE FOR RESIDUE PG4 E 607 source : DC6 53) chain E residue 37 type sequence P description BINDING SITE FOR RESIDUE TPP F 601 source : DC7 54) chain E residue 61 type sequence E description BINDING SITE FOR RESIDUE TPP F 601 source : DC7 55) chain E residue 87 type sequence P description BINDING SITE FOR RESIDUE TPP F 601 source : DC7 56) chain E residue 91 type sequence N description BINDING SITE FOR RESIDUE TPP F 601 source : DC7 57) chain E residue 124 type sequence Q description BINDING SITE FOR RESIDUE TPP F 601 source : DC7

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