eF-site ID 4rji-D PDB Code 4rji Chain D click to enlarge Title Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form I Classification LYASE Compound Acetolactate synthase Source Bacillus subtilis PY79 (V5MX36_BACIU) Sequence D:  KNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGP EIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLA TGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNAALFQ PITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQ DVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKL PVVLVGMKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTLS RDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEYD PKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTI NHIEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKSD RAHPLEIVKELRNAVDDHVTVTCDIGSHAIWMSRYFRSYE PLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGG FLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYN RTSAVDFGNIDIVKYAESFGATGLRVESPDQLADVLRQGM NAEGPVIIDVPVDYSDNINLASDKLPKEFGELMKT Description Functional site 1) chain D residue 37 type sequence P description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 2) chain D residue 61 type sequence E description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 3) chain D residue 87 type sequence P description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 4) chain D residue 91 type sequence N description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 5) chain D residue 124 type sequence Q description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 6) chain D residue 399 type sequence G description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 7) chain D residue 400 type sequence S description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 8) chain D residue 401 type sequence H description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 9) chain D residue 424 type sequence Q description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 10) chain D residue 426 type sequence L description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 11) chain D residue 450 type sequence G description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 12) chain D residue 451 type sequence D description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 13) chain D residue 452 type sequence G description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 14) chain D residue 453 type sequence G description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 15) chain D residue 478 type sequence D description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 16) chain D residue 480 type sequence T description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 17) chain D residue 481 type sequence Y description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 18) chain D residue 482 type sequence D description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 19) chain D residue 483 type sequence M description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 20) chain D residue 484 type sequence V description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 21) chain D residue 547 type sequence Y description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 22) chain D residue 451 type sequence D description BINDING SITE FOR RESIDUE MG D 1001 source : AC9 23) chain D residue 478 type sequence D description BINDING SITE FOR RESIDUE MG D 1001 source : AC9 24) chain D residue 480 type sequence T description BINDING SITE FOR RESIDUE MG D 1001 source : AC9

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