eF-site ID 4rji-C PDB Code 4rji Chain C click to enlarge Title Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form I Classification LYASE Compound Acetolactate synthase Source Bacillus subtilis PY79 (V5MX36_BACIU) Sequence C:  KNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGP EIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLA TGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNAALFQ PITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQ DVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKL PVVLVGMKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTLS RDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEYD PKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTI NHIEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKSD RAHPLEIVKELRNAVDDHVTVTCDIGSHAIWMSRYFRSYE PLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGG FLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYN RTSAVDFGNIDIVKYAESFGATGLRVESPDQLADVLRQGM NAEGPVIIDVPVDYSDNINLASDKLPKEFGELMKT Description Functional site 1) chain C residue 162 type sequence G description BINDING SITE FOR RESIDUE PG4 B 603 source : AC5 2) chain C residue 191 type sequence P description BINDING SITE FOR RESIDUE PG4 B 603 source : AC5 3) chain C residue 400 type sequence S description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 4) chain C residue 401 type sequence H description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 5) chain C residue 424 type sequence Q description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 6) chain C residue 450 type sequence G description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 7) chain C residue 451 type sequence D description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 8) chain C residue 452 type sequence G description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 9) chain C residue 453 type sequence G description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 10) chain C residue 478 type sequence D description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 11) chain C residue 480 type sequence T description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 12) chain C residue 481 type sequence Y description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 13) chain C residue 482 type sequence D description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 14) chain C residue 483 type sequence M description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 15) chain C residue 484 type sequence V description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 16) chain C residue 547 type sequence Y description BINDING SITE FOR RESIDUE TPP C 1000 source : AC6 17) chain C residue 451 type sequence D description BINDING SITE FOR RESIDUE MG C 1001 source : AC7 18) chain C residue 478 type sequence D description BINDING SITE FOR RESIDUE MG C 1001 source : AC7 19) chain C residue 480 type sequence T description BINDING SITE FOR RESIDUE MG C 1001 source : AC7 20) chain C residue 36 type sequence I description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 21) chain C residue 37 type sequence P description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 22) chain C residue 61 type sequence E description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 23) chain C residue 87 type sequence P description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 24) chain C residue 91 type sequence N description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8 25) chain C residue 124 type sequence Q description BINDING SITE FOR RESIDUE TPP D 1000 source : AC8

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