eF-site ID 4rf1-A PDB Code 4rf1 Chain A click to enlarge Title Crystal structure of the Middle-East respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group P63) Classification PROTEIN BINDING Compound ORF1ab protein Source Human betacoronavirus 2c Jordan-N3/2012 (RL40_HUMAN) Sequence A:  LTIEVLVTVDGVNFRTVVLNNKNTYRSQLGCVFFNGADIS DTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLH RFYSLKAAVHGWKMVVCDKVRSLKLSDNNCYLNAVIMTLD LLKDIKFVIPALQHAFMKHKGGDSTDFIALIMAYGNCTFG APDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVL QGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQLVEHTT PWLLLSGTPNEKLVTTSTAPDFVAFNVFQGIETAVGHYVH ARLKLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDCN Description (1)  ORF1ab protein, Ubiquitin-60S ribosomal protein L40 Functional site 1) chain A residue 1672 type sequence C description BINDING SITE FOR RESIDUE ZN A 1901 source : AC1 2) chain A residue 1675 type sequence C description BINDING SITE FOR RESIDUE ZN A 1901 source : AC1 3) chain A residue 1707 type sequence C description BINDING SITE FOR RESIDUE ZN A 1901 source : AC1 4) chain A residue 1709 type sequence C description BINDING SITE FOR RESIDUE ZN A 1901 source : AC1 5) chain A residue 1574 type sequence W description BINDING SITE FOR RESIDUE PGO A 1902 source : AC2 6) chain A residue 1624 type sequence G description BINDING SITE FOR RESIDUE PGO A 1902 source : AC2 7) chain A residue 1626 type sequence S description BINDING SITE FOR RESIDUE PGO A 1902 source : AC2 8) chain A residue 1627 type sequence T description BINDING SITE FOR RESIDUE PGO A 1902 source : AC2 9) chain A residue 1658 type sequence A description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 10) chain A residue 1659 type sequence E description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 11) chain A residue 1660 type sequence L description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 12) chain A residue 1684 type sequence G description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 13) chain A residue 1685 type sequence L description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 14) chain A residue 1686 type sequence K description BINDING SITE FOR RESIDUE PGO A 1903 source : AC3 15) chain A residue 1565 type sequence Y description BINDING SITE FOR RESIDUE PGO A 1904 source : AC4 16) chain A residue 1568 type sequence K description BINDING SITE FOR RESIDUE PGO A 1904 source : AC4 17) chain A residue 1517 type sequence N description BINDING SITE FOR RESIDUE PGO A 1905 source : AC5 18) chain A residue 1536 type sequence Y description BINDING SITE FOR RESIDUE PGO A 1905 source : AC5 19) chain A residue 1715 type sequence R description BINDING SITE FOR RESIDUE PGO A 1906 source : AC6 20) chain A residue 1590 type sequence N description BINDING SITE FOR RESIDUE 3CN B 101 source : AC7 21) chain A residue 1592 type sequence C description BINDING SITE FOR RESIDUE 3CN B 101 source : AC7 22) chain A residue 1758 type sequence G description BINDING SITE FOR RESIDUE 3CN B 101 source : AC7 23) chain A residue 1759 type sequence H description BINDING SITE FOR RESIDUE 3CN B 101 source : AC7

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