eF-site ID 4rec-A PDB Code 4rec Chain A click to enlarge Title A nuclease-DNA complex form 3 Classification Hydrolase/DNA Compound Fanconi-associated nuclease 1 Source Homo sapiens (Human) (4REC) Sequence A:  EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQL SATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEEL TNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPN GQKQQLVDAFLKLAKQKPGIGAVILKRAKALAGQSVRICK GPRAVFSRILLLFSLTDSMEDEGLLVNLGRMEFPSYTINR KTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELA QCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILS RFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRL ALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAV RLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCSVEE LALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIP DVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEE SLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLG GPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEV KGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV Description Functional site 1) chain A residue 982 type sequence R description BINDING SITE FOR RESIDUE IOD A 1101 source : AC1 2) chain A residue 741 type sequence G description BINDING SITE FOR RESIDUE IOD A 1103 source : AC2 3) chain A residue 990 type sequence W description BINDING SITE FOR RESIDUE IOD A 1103 source : AC2 4) chain A residue 834 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q9I2N0 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 960 type BINDING sequence A description BINDING => ECO:0000250|UniProtKB:Q9I2N0 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 975 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q9I2N0 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 976 type BINDING sequence V description BINDING => ECO:0000250|UniProtKB:Q9I2N0 source Swiss-Prot : SWS_FT_FI1

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